电离辐射暴露者及其后代的长期遗传和表观遗传疾病(综述)。

Problemy radiatsiinoi medytsyny ta radiobiolohii Pub Date : 2021-12-01 DOI:10.33145/2304-8336-2021-26-36-56

O V Kucher, S V Vydyborets

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引用次数: 1

摘要

本文综述了暴露个体及其后代的长期遗传和表观遗传疾病，即切尔诺贝利核电站事故清理工人及其子女的细胞遗传学影响，DNA甲基化作为人类基因组的表观遗传修饰。综述中提出的数据扩大了对当代和后代长期暴露风险的理解，这是基础辐射遗传学和人类放射生物学提出的关键问题之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

LONG/TERM GENETIC AND EPIGENETIC DISORDERS IN PERSONS EXPOSED TO IONIZING RADIATION AND THEIR DESCENDANTS (review).

The review is devoted to long-term genetic and epigenetic disorders in exposed individuals and their descendants,namely to cytogenetic effects in the Chornobyl NPP accident clean-up workers and their children, DNA methylation as an epigenetic modification of human genome. Data presented in review expand the understanding of risk of the prolonged exposure for the present and future generations, which is one of key problems posed by fundamental radiation genetics and human radiobiology.

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来源期刊

Problemy radiatsiinoi medytsyny ta radiobiolohii Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

0.60

自引率

0.00%

发文量