[18F]FDG PET-CT评估同步型乳腺癌不同糖代谢行为与组织型的关系。

Pub Date : 2022-01-01 DOI:10.5603/NMR.a2022.0012

Pietro Bellini, Domenico Albano, Francesco Dondi, Francesco Bertagna, Raffaele Giubbini

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引用次数: 1

摘要

在大多数侵袭性肿瘤中，葡萄糖代谢增加，通常通过正电子发射断层扫描-计算机断层扫描(PET-CT)与18F-氟脱氧葡萄糖([18F]FDG)进行评估，测量最大标准化摄取值(SUVmax)进行评估。特别是，已知乳腺癌表达不同的糖代谢与雌激素受体(ER)、孕激素受体(PR)、Ki67评分、肿瘤分级、肿瘤大小和人表皮生长因子受体2 (HER2)有关。我们提出一个有趣的情况下，一名妇女与两种不同的，同步乳腺癌的特点是不同的葡萄糖代谢，根据文献知识。

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Different glucose metabolism behavior relating to histotypes in synchronous breast cancers evaluated by [18F]FDG PET-CT.

Glucose metabolism is increased in most aggressive tumors and it is commonly evaluated by positron emission tomography-computed tomography (PET-CT) with 18F-fluorodeoxyglucose ([18F]FDG), measuring the Maximum Standardized Uptake Value (SUVmax) for the assessment. Particularly, it is known that breast cancer expresses different glucose metabolism inrelation to estrogen receptor (ER), progesterone receptor (PR), Ki67 score, tumor grading, tumor size, and Human Epidermal Growth Factor Receptor 2 (HER2). We present an interesting case of a woman with two different, synchronous breast cancers characterized by different glucose metabolism, according to literature knowledge.

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