2021年8月至9月荷兰Delta变体(B.1.617.2)占主导地位期间防止SARS-CoV-2向家庭接触者传播的疫苗有效性

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin Pub Date : 2021-11-01 DOI:10.2807/1560-7917.ES.2021.26.44.2100977

Brechje de Gier, Stijn Andeweg, Jantien A Backer, Susan Jm Hahné, Susan van den Hof, Hester E de Melker, Mirjam J Knol

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引用次数: 72

摘要

我们通过比较接种疫苗和未接种疫苗的指示病例的家庭成员的二次发病率，根据在Delta变体占主导地位时收集的来源和接触者追踪数据，估计了SARS-CoV-2疫苗对进一步传播的有效性。除了直接保护接触者接种疫苗免受感染外，指示病例全面接种疫苗防止传播给未接种疫苗和完全接种疫苗的家庭接触者的有效性分别为63%(95%置信区间(CI): 46-75)和40% (95% CI: 20-54)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021.

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Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021.

We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46-75) and 40% (95% CI: 20-54), in addition to the direct protection of vaccination of contacts against infection.

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Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

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