膀胱镜下局灶性和弥漫性血管增生对预测膀胱疼痛综合征患者膀胱内治疗反应的影响。

IF 1 Q4 UROLOGY & NEPHROLOGY
Bulent Erol, Huseyin Ozgur Kazan, Ferhat Keser, Ozgur Efiloglu, Yavuz Onur Danacıoğlu, Rahmi Onur
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引用次数: 2

摘要

目的:探讨膀胱疼痛综合征/间质性膀胱炎(BPS/IC)的膀胱镜表现(包括血管增生等新表现)与膀胱内治疗反应之间的关系。材料和方法:我们回顾性评估初步诊断为BPS/IC的患者的膀胱镜检查结果。所有患者均接受早期膀胱内联合治疗(ICT),即在腹水膨胀后2小时内。此外,ICT按照我们的方案继续进行。膀胱镜检查结果分为肾小球、血管增生和Hunner病变(HL)。采用视觉模拟量表(VAS)、O’leary /Sant间质性膀胱炎症状指数(ICSI)和间质性膀胱炎问题指数(ICPI)评分,在第1、3、6和12个月评估治疗效果。结果:61例患者中,6例(9.8%)患者在膀胱镜检查中被诊断为HL, 35例(57.4%)患者被诊断为肾小球,15例(24.6%)患者被诊断为血管增生。5例(8.2%)患者未见病理表现。在肾小球和血管增生组,随访时VAS、ICSI和ICPI的中位评分均低于术前。HL患者的VAS评分中位数在整个随访期间均低于术前,第1年较第6个月升高,ICSI评分在整个随访期间均低于术前,第3个月和第1年均升高。ICPI评分在随访期间也较低,在第一年观察到增加。结论:血管增生的存在应该被定义,因为它可能表现出不同的特征,可能影响ICT的反应。肾小球患者可能是早期联合膀胱内治疗的好人选。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Effect of focal and diffuse hypervascularization as cystoscopic findings on predicting intravesical therapy response in patients with bladder pain syndrome.

Effect of focal and diffuse hypervascularization as cystoscopic findings on predicting intravesical therapy response in patients with bladder pain syndrome.

Effect of focal and diffuse hypervascularization as cystoscopic findings on predicting intravesical therapy response in patients with bladder pain syndrome.

Effect of focal and diffuse hypervascularization as cystoscopic findings on predicting intravesical therapy response in patients with bladder pain syndrome.

Objective: To define the relationship between cystoscopic findings, including novel findings such as the hypervascularization, of bladder pain syndrome/interstitial cystitis (BPS/IC) and the response to intravesical therapy.

Material and methods: We retrospectively evaluated cystoscopy findings in patients who had a preliminary diagnosis of BPS/IC. All patients received early intravesical combined therapy (ICT), ie, within 2 hours after hydrodistention. Additionally, ICT was continued according to our protocol. Cystoscopic findings were classified as glomerulations, hypervascularization, and Hunner's lesion (HL). The therapy responses were evaluated at 1st, 3rd, 6th, and 12thmonths using the visual analog scale (VAS), O'Leary/Sant interstitial cystitis symptom index (ICSI), and interstitial cystitis problem index (ICPI) scores.

Results: Out of 61 patients, HL was diagnosed during cystoscopy in six (9.8%) patients, glomerulations in 35 (57.4%) patients, and hypervascularization in 15 (24.6%) patients. No pathological findings were defined in five (8.2%) patients. In the glomerulation and hypervascularization group, the median VAS, ICSI, and ICPI scores were lower than those in the preoperative period in the follow-up. In patients with HL, the median VAS scores were lower in the entire follow-up compared to the preoperative period, with an increase at 1st year compared to 6th month, and ICSI scores were lower than preoperative period in the entire follow-up, with an increase at 3rd month and 1st year. ICPI scores were also lower during the follow-up, with an increase observed in the 1st year.

Conclusion: The presence of hypervascularization should be defined since it might show different characteristics that may affect the ICT response. Patients with glomerulations might be good candidates for early combined intravesical therapy.

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来源期刊
Turkish journal of urology
Turkish journal of urology Medicine-Urology
CiteScore
2.10
自引率
0.00%
发文量
53
期刊介绍: The aim of the Turkish Journal of Urology is to contribute to the literature by publishing scientifically high-quality research articles as well as reviews, editorials, letters to the editor and case reports. The journal’s target audience includes, urology specialists, medical specialty fellows and other specialists and practitioners who are interested in the field of urology.
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