光学相干层析成像的研究进展。

4区 医学 Q3 Medicine
Hautarzt Pub Date : 2021-12-01 Epub Date: 2021-10-26 DOI:10.1007/s00105-021-04905-2
Cristel Ruini, Fabia Daxenberger, Charlotte Gust, Sandra Schuh, Lars E French, Julia Welzel, Elke C Sattler
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引用次数: 2

摘要

近年来,光学相干断层扫描(OCT)不仅在学术科学领域,而且在日常皮肤医学实践中也得到了广泛的应用。它的重点是皮肤上皮性肿瘤,可以直观地在几秒钟内诊断出来。因此,基底细胞癌、光化性角化病和不同阶段的野区癌可以被诊断和监测对治疗的反应或可能的复发。这通常有助于避免侵入性取样。最近,OCT领域及其最新进展,动态OCT (D-OCT),已经扩展到包括非肿瘤性皮肤疾病。这包括炎症性皮肤病和皮肤生理参数的分析,如水合作用。由于自动化血管成像和测量客观参数,如表皮厚度、深度血流、光学衰减系数和皮肤粗糙度,越来越多的皮肤特征可以以无创和标准化的方式进行研究。新的潜在应用领域是湿疹,接触性过敏性皮炎,牛皮癣,酒痤疮,毛细血管扩张,急性和慢性伤口,黄褐斑和红痣,以及黑素细胞病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Advances in optical coherence tomography].

Optical coherence tomography (OCT) has been able to establish itself in recent years not only in academic-scientific, but also in everyday dermatological practice. Its focus lies on epithelial tumors of the skin, which can be diagnosed intuitively and within a few seconds. Thus, basal cell carcinomas, actinic keratoses, and different stages of field cancerization can be diagnosed and monitored for response to therapy or possible recurrence. This often helps to avoid invasive sample extraction. Recently, the field of OCT and its latest advancement, dynamic OCT (D-OCT), has been expanded to include non-oncologic dermatological diseases. This encompasses inflammatory dermatoses and the analysis of physiological skin parameters such as hydration. Thanks to automated vascular imaging and the measurement of objective parameters such as epidermal thickness, blood flow at depth, optical attenuation coefficient, and skin roughness, more and more characteristics of the skin can be studied in a noninvasive and standardized way. New potential areas of application are eczema, contact allergic dermatitis, psoriasis, rosacea, telangiectasia, acute and chronic wounds, melasma and nevus flammeus but also melanocytic lesions.

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来源期刊
Hautarzt
Hautarzt 医学-皮肤病学
CiteScore
1.40
自引率
0.00%
发文量
93
审稿时长
4-8 weeks
期刊介绍: Der Hautarzt is an internationally recognized journal informing all dermatologists working in practical or clinical environments about important developments in the field of dermatology including allergology, venereology and related areas. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice.
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