新方法重建旧挑战:整块移植物在男性生殖器坏死性软组织感染中的应用。

Case Reports in Urology Pub Date : 2021-10-07 eCollection Date: 2021-01-01 DOI:10.1155/2021/5777235
Katharina Mitchell, Chad Crigger, Chad Morley, John Barnard, Vidas Dumasius
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引用次数: 1

摘要

在本文中,我们描述了两例富尼耶坏疽(FG),其中Integra移植用于重建。FG是一种进行性坏死性感染,发生于会阴区和外生殖器。由于这种感染对软组织的破坏,使用局部组织的重建选择是有限的。Integra移植物是由鲨鱼6-硫酸软骨素和牛胶原蛋白制成的双胺酸人工真皮。适用于创面清创后的伤口床,建立健康、血管通畅的创面基础。在这个病例系列的患者有很大的缺陷,不能主要与组织床关闭,将不适合皮肤移植。因此,植入Integra移植物。两例患者术后3周创面均适合植皮。如果没有Integra移植物,我们的两名患者在重建前都需要等待相当长的时间。我们的病例系列进一步说明并支持Integra移植物在富尼耶坏疽后的这种情况下的使用,这种情况之前只发表过三次,所有这些都显示出成功的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

New Methods of Reconstruction for Old Challenges: The Use of the Integra Graft in Necrotizing Soft Tissue Infections of the Male Genitalia.

New Methods of Reconstruction for Old Challenges: The Use of the Integra Graft in Necrotizing Soft Tissue Infections of the Male Genitalia.

New Methods of Reconstruction for Old Challenges: The Use of the Integra Graft in Necrotizing Soft Tissue Infections of the Male Genitalia.

New Methods of Reconstruction for Old Challenges: The Use of the Integra Graft in Necrotizing Soft Tissue Infections of the Male Genitalia.

In this paper, we describe two cases of Fournier's gangrene (FG) in which Integra grafting was used for reconstruction. FG is a progressive necrotizing infection occurring in the perineal region and on the external genitalia. Reconstructive options using local tissue are limited due to the destruction this infection imposes on the soft tissue. Integra graft is a bilaminate artificial dermis made of shark chondroitin 6-sulfate and bovine collagen. It is applied to the wound bed after debridement and establishment of a healthy, well-vascularized wound base. The patients in this case series had large defects which could not be closed primarily with tissue beds and would not have been appropriate for skin grafting. Therefore, an Integra graft was placed. In both patients, the wound beds were appropriate for skin grafting after three weeks. Without the Integra graft, both of our patients would have needed to wait a considerable amount of time prior to reconstruction. Our case series further illustrates and supports the use of Integra grafts in such a scenario following Fournier's gangrene which has only previously been published on three occasions, all of which demonstrated successful outcomes.

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