Primary sulfonamide-functional polymers with controlled chain architectures by RAFT polymerisation†

RAFT polymerization allows the synthesis of well-defined (co)polymer architectures comprising primary benzene sulfonamide groups, either using an acrylamido sulfonamide monomer or a sulfonamide-functional trithiocarbonate RAFT agent. This work unlocks the potential for accessing a new generation of pH-responsive block copolymers and functional polymeric vectors with targeting properties for biomedical applications.