吗啡生物碱:历史、生物学和合成。

Q1 Biochemistry, Genetics and Molecular Biology

Alkaloids: Chemistry and Biology Pub Date : 2021-01-01 Epub Date: 2021-09-21 DOI:10.1016/bs.alkal.2021.04.001

Christopher Wicks, Tomas Hudlicky, Uwe Rinner

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引用次数: 10

摘要

本章简要概述了吗啡自1805年被sert rner分离以来的历史。详细讨论了标题生物碱的生物合成以及1996年以后发表的吗啡和可待因的总合成和正式合成。本章的最后一节提供了标题生物碱的医学相关衍生物的详细概述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Morphine alkaloids: History, biology, and synthesis.

This chapter provides a short overview of the history of morphine since it's isolation by Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal syntheses of morphine and codeine published after 1996 are discussed in detail. The last section of this chapter provides a detailed overview of medicinally relevant derivatives of the title alkaloid.

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来源期刊

Alkaloids: Chemistry and Biology Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

13.70

自引率

0.00%

发文量