绒毛膜癌转移到皮肤:一种罕见的发生与令人沮丧的结果。

IF 0.9 Q4 ONCOLOGY
Rare Tumors Pub Date : 2021-08-20 eCollection Date: 2021-01-01 DOI:10.1177/20363613211039724
Mousa ElKhaldi, Rakan Radi, Maysa Al-Hussaini
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引用次数: 0

摘要

生殖细胞肿瘤(gct)是一种组织学异质性的肿瘤,起源于胚胎性腺的原始生殖细胞。绒毛膜癌是gct的一种变体,容易发生肝、肺和脑的血液转移。绒毛膜癌的皮肤转移是罕见的,文献报道的病例很少。我们报告的情况下,一个28岁的男性提出腰痛,经进一步检查,被诊断为纯绒毛膜癌的睾丸。初次就诊后约9个月,患者出现背部皮肤病变。显微镜检查证实绒毛膜癌由单核细胞滋养细胞与多核合胞滋养细胞交织而成。患者于发生皮肤转移后3周死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Choriocarcinoma metastatic to the skin: A rare occurrence associated with dismal outcome.

Choriocarcinoma metastatic to the skin: A rare occurrence associated with dismal outcome.

Choriocarcinoma metastatic to the skin: A rare occurrence associated with dismal outcome.

Choriocarcinoma metastatic to the skin: A rare occurrence associated with dismal outcome.

Germ cell tumors (GCTs) are a histologically heterogeneous group of tumors that arise from the primitive germ cell of the embryonic gonad. Choriocarcinoma is a variant of GCTs that is prone to hematogenous metastasis to the liver, lung, and brain. Cutaneous metastasis in choriocarcinoma is rarely encountered with only a few cases reported in literature. We report the case of a 28-year-old male presenting with lower back pain that, upon further work-up, was diagnosed with pure choriocarcinoma of the testes. Around 9 months after his initial presentation, he developed a cutaneous back lesion. Microscopic examination confirmed the presence of choriocarcinoma composed of mononuclear cytotrophoblasts which interweave with multinucleated syncytiotrophoblasts. The patient passed away 3 weeks after the onset of cutaneous metastasis.

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Rare Tumors
Rare Tumors ONCOLOGY-
CiteScore
1.50
自引率
0.00%
发文量
15
审稿时长
15 weeks
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