艾伯塔省口腔和口咽癌的监测和控制:范围审查。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2021-01-01

Parvaneh Badri, Seema Ganatra, Vickie Baracos, Hollis Lai, Maryam S Amin

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引用次数: 0

摘要

目的:这一范围审查提供了一个全面的概述口腔癌(OCC)和口咽癌(OPC)在艾伯塔省。方法:使用Web of Science、Scopus、Medline、PubMed和Embase进行截至2018年的数据库检索，并手动检索灰色文献。数据来自艾伯塔省癌症基金会的专门研究基金、癌症监测和报告以及艾伯塔省癌症登记处。结果:我们的综述包括8篇已发表的论文和14个其他来源，包括来自监测和报告和艾伯塔省癌症登记处的3448例OCC和OPC患者的数据。癌症登记数据(2005-2017)显示，大多数OCC和OPC病变在临床晚期诊断，晚期OPC病变在IV期显著增多(OCC 45.2%， OPC 82.4%);47.9%的患者死亡。农村和第一民族地区的存活率最低。在艾伯塔省，35%的hpv相关癌症与OPCs有关，OPCs在男性和年轻年龄组中更为普遍。目前在艾伯塔省没有常规的公共口腔癌筛查项目。全科医生和牙医将病人转诊给专科医生，通常要等很长时间。结论:艾伯塔省的OCC和OPC患者继续被诊断为IV期，死亡率很高。

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Oral Cavity and Oropharyngeal Cancer Surveillance and Control in Alberta: A Scoping Review.

Objectives: This scoping review provides a comprehensive overview of oral cavity cancer (OCC) and oropharyngeal cancer (OPC) in Alberta.

Methods: A database search was conducted up to 2018 using Web of Science, Scopus, Medline, PubMed and Embase, along with a manual search of gray literature. Data from the Alberta Cancer Foundation's dedicated fund for research, Cancer Surveillance and Reporting and Alberta Cancer Registry were also collected.

Results: Our review included 8 published papers and 14 other sources, including data on 3448 OCC and OPC patients from Surveillance and Reporting and Alberta Cancer Registry. Cancer registry data (2005-2017) showed that most OCC and OPC lesions were diagnosed at an advanced clinical stage, with a significantly large number of advanced OPC lesions in stage IV (OCC 45.2%, OPC 82.4%); 47.9% of these patients died. Survival rates were lowest in rural and First Nations areas. In Alberta, 35% of HPV-associated cancers were linked to OPCs, which were more prevalent in men and younger age groups. No routine public oral cancer screening program currently exists in Alberta. General practitioners and dentists refer patients to specialists, often with long waiting times.

Conclusion: OCC and OPC patients in Alberta continue to be diagnosed in stage IV and experience high mortality rates.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.