Ahmed A Abood, Ole Rahbek, Morten L Olesen, Bjørn B Christensen, Bjarne Møller-Madsen, Søren Kold
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No osseous tissue crossing the physis was observed on MRI or histology. The empty canal in the physis after nail removal was filled with fibrous tissue 16 weeks after primary surgery.</p><p><strong>Conclusion: </strong>Growth was not impaired and no bone bridges were seen on MRI or histology 16 weeks after insertion and later removal of the retrograde femoral nail.</p><p><strong>Clinical significance: </strong>The insertion of a retrograde intramedullary femoral nail centrally through the physis and later removal might be safe, however, long-term follow-up is needed.</p><p><strong>Aim and objective: </strong>The insertion of an intramedullary nail may be beneficial in certain cases of leg length discrepancy (LLD) in children. However, it is unknown if the physeal injury due to the surgery may cause bone bridge formation and thereby growth arrest after removal. This study aimed to assess longitudinal interphyseal growth 16 weeks after insertion and later removal of a retrograde femoral nail passing through the physis. Moreover, to analyse the tissue forming in the empty physeal canal after removal of the nail.</p><p><strong>How to cite this article: </strong>Abood AA, Rahbek O, Olesen ML, <i>et al</i>. Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model. Strategies Trauma Limb Reconstr 2021;16(1):8-13.</p>","PeriodicalId":21979,"journal":{"name":"Strategies in Trauma and Limb Reconstruction","volume":"16 1","pages":"8-13"},"PeriodicalIF":1.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/4c/stlr-16-8.PMC8311745.pdf","citationCount":"1","resultStr":"{\"title\":\"Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? 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引用次数: 1
摘要
材料与方法:采用实验猪模型进行研究。随机选取11头幼年母猪，在其一侧肢体植入逆行股内钉。另一条肢体作为对照。拔钉前饲养8周，再饲养8周，共16周。16周后通过三维磁共振成像(MRI)的骨骺间距离评估生长情况，并将手术肢体与未手术肢体进行比较。对椎管进行组织形态学分析。结果:16周后MRI对比手术股骨与未手术股骨纵向生长无差异。MRI及组织学未见骨组织横过。初次手术后16周，拔除指甲后的躯体空管被纤维组织填充。结论:逆行股钉插入和取出16周后，生长未受损，MRI和组织学未见骨桥。临床意义:逆行股髓内钉经物理中心插入和取出可能是安全的，但需要长期随访。目的和目的:髓内钉的插入可能是有益的，在某些情况下，腿长差异(LLD)的儿童。然而，目前尚不清楚手术造成的骨骺损伤是否会导致骨桥形成，从而导致骨桥切除后生长停止。本研究旨在评估穿过骨骺的逆行股钉插入和取出16周后的纵向骨骺间生长情况。此外，还分析了拔钉后空椎管内的组织形成情况。如何引用本文:Abood AA, Rahbek O, Olesen ML等。逆行股内钉穿过正常身体会影响生长吗?实验猪模型。创伤肢体重建，2016;16(1):8-13。
Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model.
Materials and methods: The study was carried out using an experimental porcine model. Eleven juvenile female porcines were randomized for insertion of a retrograde femoral nail in one limb. The other limb acted as a control. The animals were housed for 8 weeks before the nail was removed and housed for 8 additional weeks, that is, 16 weeks in total. Growth was assessed by interphyseal distance on 3D magnetic resonance imaging (MRI) after 16 weeks and the operated limb was compared to the non-operated limb. Histomorphometric analysis of the physeal canal was performed.
Results: No difference in longitudinal growth was observed when comparing the operated femur to the non-operated femur using MRI after 16 weeks. No osseous tissue crossing the physis was observed on MRI or histology. The empty canal in the physis after nail removal was filled with fibrous tissue 16 weeks after primary surgery.
Conclusion: Growth was not impaired and no bone bridges were seen on MRI or histology 16 weeks after insertion and later removal of the retrograde femoral nail.
Clinical significance: The insertion of a retrograde intramedullary femoral nail centrally through the physis and later removal might be safe, however, long-term follow-up is needed.
Aim and objective: The insertion of an intramedullary nail may be beneficial in certain cases of leg length discrepancy (LLD) in children. However, it is unknown if the physeal injury due to the surgery may cause bone bridge formation and thereby growth arrest after removal. This study aimed to assess longitudinal interphyseal growth 16 weeks after insertion and later removal of a retrograde femoral nail passing through the physis. Moreover, to analyse the tissue forming in the empty physeal canal after removal of the nail.
How to cite this article: Abood AA, Rahbek O, Olesen ML, et al. Does Retrograde Femoral Nailing through a Normal Physis Impair Growth? An Experimental Porcine Model. Strategies Trauma Limb Reconstr 2021;16(1):8-13.
期刊介绍：
Strategies in Trauma and Limb Reconstruction is dedicated to surgeons, allied medical professionals and researchers in the field of orthopaedics and trauma. The scope of the journal is to discuss the fields of skeletal injury, and the complications thereof, congenital and acquired limb deformities and deficiencies, and orthopaedic-related infection, together with their surgical and non-surgical treatments. The journal publishes original articles, reviews, case reports, descriptions of new or recognised treatment techniques, forum discussions of clinical scenarios and relevant correspondence. It aims to provide a widely accessible source of useful information to practitioners in the field through the problem- or technique-based approach of published articles.
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