扩大赖氨酸产业:以生物技术生产赖氨酸及其衍生物。

2区生物学 Q1 Immunology and Microbiology

Advances in applied microbiology Pub Date : 2021-01-01 Epub Date: 2021-03-18 DOI:10.1016/bs.aambs.2021.02.001

Jiaping Wang, Cong Gao, Xiulai Chen, Liming Liu

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引用次数: 3

摘要

赖氨酸是一种必需氨基酸，含有α-氨基、ω-氨基、α-羧基等多种官能团，具有较高的反应电位。这些官能团的衍生化产生一系列增值化学品，如尸胺、戊二酸盐、d-赖氨酸等，广泛应用于化学合成、化妆品、食品和制药等行业。本文综述了生物技术生产赖氨酸及其衍生物的最新进展，并阐述了关键技术策略。此外，我们还讨论了现有的挑战和更有效地生产这些化学品的潜在战略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Expanding the lysine industry: biotechnological production of l-lysine and its derivatives.

l-lysine is an essential amino acid that contains various functional groups including α-amino, ω-amino, and α-carboxyl groups, exhibiting high reaction potential. The derivatization of these functional groups produces a series of value-added chemicals, such as cadaverine, glutarate, and d-lysine, that are widely applied in the chemical synthesis, cosmetics, food, and pharmaceutical industries. Here, we review recent advances in the biotechnological production of l-lysine and its derivatives and expatiate key technological strategies. Furthermore, we also discuss the existing challenges and potential strategies for more efficient production of these chemicals.

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来源期刊

Advances in applied microbiology 生物-生物工程与应用微生物

CiteScore

8.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays.