筛选抑郁的潜在生物库捐献者对披露个人健康结果的态度。

IF 1.1 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annali dell'Istituto superiore di sanita Pub Date : 2021-04-01 DOI:10.4415/ANN_21_02_05

Virgilia Toccaceli, Corrado Fagnani, Antonella Gigantesco, Angelo Picardi, Maria Antonietta Stazi

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引用次数: 1

摘要

背景:基于与健康和临床数据相关的生物材料的研究可能产生疾病预防、诊断和治疗的新策略。本研究以重度抑郁症(MDD)患者为调查对象，探讨他们对研究生物银行的态度。方法:采用自述式问卷调查，问卷内容包括捐赠研究用生物库、自我感知健康和生活满意度。各组间均值和百分比比较采用t检验、方差分析和卡方检验。结果:在接受重度抑郁症筛查的416名受试者中，51名(12.2%)回应了调查，其中大多数(42名)同意仅在没有关于健康或疾病的反馈的情况下使用他们的生物样本。对生物银行的认同不受生活满意度或自我感知健康的影响。结论:我们的研究结果显示，在mdd筛查的受试者中，普遍倾向于不愿披露健康结果，这表明个人因素——尤其是社会心理因素——在研究生物库个人的贡献中发挥了作用。

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Attitude of potential biobank donors screened for depression towards disclosure of individual health results.

Background: Research based on biological material with linked health and clinical data may produce new strategies for disease prevention, diagnosis and treatment. A survey was conducted among individuals previously screened for major depressive disorder (MDD) to explore participants' attitude towards research biobanking.

Methods: The survey used self-report questionnaires about donation for research biobanks, self-perceived health and life satisfaction. Means and percentages were compared across groups by using t test, ANOVA and chi-square test.

Results: Of 416 subjects who underwent the MDD screening, 51 (12.2%) responded to the survey, with the majority of them (42) agreeing to the use of their biological samples only in absence of feedbacks about health or diseases. Agreement towards biobanking was not affected by life satisfaction or self-perceived health.

Conclusions: Our findings show a prevailing preference against health results disclosure among MDD-screened subjects, suggesting a role of personal - particularly psychosocial - factors in research biobanking individuals' contribution.

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来源期刊

Annali dell'Istituto superiore di sanita PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.80

自引率

4.80%

发文量

审稿时长

>12 weeks

期刊介绍： Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews. The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office. The journal is in English.