运用创新扩散理论理解营养遗传学在临床实践中应用的挑战和机遇。

IF 2 4区 医学 Q3 GENETICS & HEREDITY
Lifestyle Genomics Pub Date : 2021-01-01 Epub Date: 2021-07-21 DOI:10.1159/000517760
Olivia M Dong
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引用次数: 0

摘要

本文章由计算机程序翻译,如有差异,请以英文原文为准。
Using the Diffusion of Innovation Theory to Understand the Challenges and Opportunities to Advancing Use of Nutrigenetics in Clinical Practice.
The National Human Genome Research Institute (NHGRI) published bold predictions for genomic medicine to strive toward by 2030 [1]. These predictions outline a promising impact genomic information will have on health, including aspirations such as enabling individuals to securely access genome sequencing results on their smartphones and making the use of genomic information as routine in all clinical settings [1]. One application of genomic medicine is nutrigenetics (NGx), which investigates the associations between genetic variants, diet, and health outcomes [2]. NGx has the potential to use genetic information in ways that can further individualize nutrition interventions to help patients achieve improved health outcomes. While incorporating NGx testing as part of clinical care is promising, it is not routinely done in clinical settings. To better understand how NGx testing can strive toward routine use per NHGRI’s aspirational goals, the diffusion of innovation (DOI) theory will be used as a framework to examine the challenges and opportunities of integrating NGx testing into clinical care. The DOI theory seeks to explain the spread of innovations through populations and how they get adopted over time [3], with recognition that the majority of innovations fail to successfully diffuse through populations and that adoption is not necessarily based on the effectiveness of innovations [4]. In fact, effective innovations can be stalled, while ineffective innovations can sometimes diffuse farther in comparison [4]. The adoption rate for innovations relies on several factors, including the perceived attributes of the innovation, characteristics of the adopters, communication channels (e.g., mass media), and the social system (e.g., diffusion within health-care systems) [3]. The perceived attributes of NGx testing and characteristics of adopters will be discussed in more detail.
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来源期刊
Lifestyle Genomics
Lifestyle Genomics Agricultural and Biological Sciences-Food Science
CiteScore
4.00
自引率
7.70%
发文量
11
审稿时长
28 weeks
期刊介绍: Lifestyle Genomics aims to provide a forum for highlighting new advances in the broad area of lifestyle-gene interactions and their influence on health and disease. The journal welcomes novel contributions that investigate how genetics may influence a person’s response to lifestyle factors, such as diet and nutrition, natural health products, physical activity, and sleep, amongst others. Additionally, contributions examining how lifestyle factors influence the expression/abundance of genes, proteins and metabolites in cell and animal models as well as in humans are also of interest. The journal will publish high-quality original research papers, brief research communications, reviews outlining timely advances in the field, and brief research methods pertaining to lifestyle genomics. It will also include a unique section under the heading “Market Place” presenting articles of companies active in the area of lifestyle genomics. Research articles will undergo rigorous scientific as well as statistical/bioinformatic review to ensure excellence.
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