脑转移瘤的外科治疗和放射治疗。

4区医学 Q3 Medicine

Radiologe Pub Date : 2021-08-01 DOI:10.1007/s00117-021-00894-4

Jan P Boström, Kathleen Jetschke, Kirsten Schmieder, Irenä Us A Adamietz

{"title":"脑转移瘤的外科治疗和放射治疗。","authors":"Jan P Boström, Kathleen Jetschke, Kirsten Schmieder, Irenä Us A Adamietz","doi":"10.1007/s00117-021-00894-4","DOIUrl":null,"url":null,"abstract":"The aim of this work is to outline the principles of interdisciplinary treatment of brain metastases. Interdisciplinary treatment is determined by the clinical situation, anatomical conditions and tumor entity and has the goal of reducing toxicity. Magnetic resonance imaging, computed tomography (CT) and positron emission tomography-CT are used to diagnose brain metastases. Neurosurgery is used for accessible, symptomatic metastases. For localized metastases, including multiple metastases, that are surgically inaccessible, radiosurgery is used. If possible, partial brain irradiation is preferred to whole-brain irradiation. Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity. In emergency situations, steroids provide effective support and a neurosurgical intervention may be life-saving. The options for systemic drug therapy are increasing.","PeriodicalId":54513,"journal":{"name":"Radiologe","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00117-021-00894-4","citationCount":"1","resultStr":"{\"title\":\"[Surgical treatment and radiation therapy of brain metastases].\",\"authors\":\"Jan P Boström, Kathleen Jetschke, Kirsten Schmieder, Irenä Us A Adamietz\",\"doi\":\"10.1007/s00117-021-00894-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aim of this work is to outline the principles of interdisciplinary treatment of brain metastases. Interdisciplinary treatment is determined by the clinical situation, anatomical conditions and tumor entity and has the goal of reducing toxicity. Magnetic resonance imaging, computed tomography (CT) and positron emission tomography-CT are used to diagnose brain metastases. Neurosurgery is used for accessible, symptomatic metastases. For localized metastases, including multiple metastases, that are surgically inaccessible, radiosurgery is used. If possible, partial brain irradiation is preferred to whole-brain irradiation. Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity. In emergency situations, steroids provide effective support and a neurosurgical intervention may be life-saving. The options for systemic drug therapy are increasing.\",\"PeriodicalId\":54513,\"journal\":{\"name\":\"Radiologe\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/s00117-021-00894-4\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiologe\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00117-021-00894-4\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiologe","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00117-021-00894-4","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 1

摘要

这项工作的目的是概述跨学科治疗脑转移的原则。跨学科治疗是由临床情况、解剖条件和肿瘤实体决定的，以降低毒性为目标。磁共振成像、计算机断层扫描(CT)和正电子发射断层扫描(CT)被用于诊断脑转移。神经外科手术用于易接近的、有症状的转移。对于局部转移，包括多发性转移，手术无法达到，使用放射手术。如果可能，局部脑照射优于全脑照射。在全脑放射治疗期间对海马的保护可减少治疗毒性。在紧急情况下，类固醇提供有效的支持，神经外科干预可能挽救生命。全身药物治疗的选择正在增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[Surgical treatment and radiation therapy of brain metastases].

The aim of this work is to outline the principles of interdisciplinary treatment of brain metastases. Interdisciplinary treatment is determined by the clinical situation, anatomical conditions and tumor entity and has the goal of reducing toxicity. Magnetic resonance imaging, computed tomography (CT) and positron emission tomography-CT are used to diagnose brain metastases. Neurosurgery is used for accessible, symptomatic metastases. For localized metastases, including multiple metastases, that are surgically inaccessible, radiosurgery is used. If possible, partial brain irradiation is preferred to whole-brain irradiation. Protection of the hippocampus during whole-brain radiotherapy reduces therapy toxicity. In emergency situations, steroids provide effective support and a neurosurgical intervention may be life-saving. The options for systemic drug therapy are increasing.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Radiologe 医学-核医学

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Der Radiologe is an internationally recognized journal dealing with all aspects of radiology and serving the continuing medical education of radiologists in clinical and practical environments. The focus is on x-ray diagnostics, angiography computer tomography, interventional radiology, magnet resonance tomography, digital picture processing, radio oncology and nuclear medicine. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.