杂交坏死的一百年:杂交自身免疫作为植物-病原体相互作用机制和进化的窗口。

IF 9.1 1区 农林科学 Q1 PLANT SCIENCES
Annual review of phytopathology Pub Date : 2021-08-25 Epub Date: 2021-05-04 DOI:10.1146/annurev-phyto-020620-114826
Lei Li, Detlef Weigel
{"title":"杂交坏死的一百年:杂交自身免疫作为植物-病原体相互作用机制和进化的窗口。","authors":"Lei Li,&nbsp;Detlef Weigel","doi":"10.1146/annurev-phyto-020620-114826","DOIUrl":null,"url":null,"abstract":"<p><p>Hybrid necrosis in plants refers to a genetic autoimmunity syndrome in the progeny of interspecific or intraspecific crosses. Although the phenomenon was first documented in 1920, it has been unequivocally linked to autoimmunity only recently, with the discovery of the underlying genetic and biochemical mechanisms. The most common causal loci encode immune receptors, which are known to differ within and between species. One mechanism can be explained by the guard hypothesis, in which a guard protein, often a nucleotide-binding site-leucine-rich repeat protein, is activated by interaction with a plant protein that mimics standard guardees modified by pathogen effector proteins. Another surprising mechanism is the formation of inappropriately active immune receptor complexes. In this review, we summarize our current knowledge of hybrid necrosis and discuss how its study is not only informing the understanding of immune gene evolution but also revealing new aspects of plant immune signaling.</p>","PeriodicalId":8251,"journal":{"name":"Annual review of phytopathology","volume":"59 ","pages":"213-237"},"PeriodicalIF":9.1000,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"15","resultStr":"{\"title\":\"One Hundred Years of Hybrid Necrosis: Hybrid Autoimmunity as a Window into the Mechanisms and Evolution of Plant-Pathogen Interactions.\",\"authors\":\"Lei Li,&nbsp;Detlef Weigel\",\"doi\":\"10.1146/annurev-phyto-020620-114826\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Hybrid necrosis in plants refers to a genetic autoimmunity syndrome in the progeny of interspecific or intraspecific crosses. Although the phenomenon was first documented in 1920, it has been unequivocally linked to autoimmunity only recently, with the discovery of the underlying genetic and biochemical mechanisms. The most common causal loci encode immune receptors, which are known to differ within and between species. One mechanism can be explained by the guard hypothesis, in which a guard protein, often a nucleotide-binding site-leucine-rich repeat protein, is activated by interaction with a plant protein that mimics standard guardees modified by pathogen effector proteins. Another surprising mechanism is the formation of inappropriately active immune receptor complexes. In this review, we summarize our current knowledge of hybrid necrosis and discuss how its study is not only informing the understanding of immune gene evolution but also revealing new aspects of plant immune signaling.</p>\",\"PeriodicalId\":8251,\"journal\":{\"name\":\"Annual review of phytopathology\",\"volume\":\"59 \",\"pages\":\"213-237\"},\"PeriodicalIF\":9.1000,\"publicationDate\":\"2021-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"15\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annual review of phytopathology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1146/annurev-phyto-020620-114826\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/5/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual review of phytopathology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1146/annurev-phyto-020620-114826","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/5/4 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 15

摘要

植物杂交坏死是指在种间或种内杂交后代中发生的一种遗传自身免疫综合征。虽然这种现象在1920年首次被记录下来,但直到最近,随着潜在的遗传和生化机制的发现,才明确地将其与自身免疫联系起来。最常见的致病基因座编码免疫受体,已知在物种内部和物种之间存在差异。一种机制可以用保护假说来解释,其中保护蛋白,通常是核苷酸结合位点-富含亮氨酸的重复蛋白,通过与植物蛋白相互作用而被激活,该植物蛋白模仿被病原体效应蛋白修饰的标准保护蛋白。另一个令人惊讶的机制是形成不适当活跃的免疫受体复合物。在这篇综述中,我们总结了我们目前对杂交坏死的认识,并讨论了它的研究如何不仅为免疫基因进化的理解提供信息,而且揭示了植物免疫信号传导的新方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
One Hundred Years of Hybrid Necrosis: Hybrid Autoimmunity as a Window into the Mechanisms and Evolution of Plant-Pathogen Interactions.

Hybrid necrosis in plants refers to a genetic autoimmunity syndrome in the progeny of interspecific or intraspecific crosses. Although the phenomenon was first documented in 1920, it has been unequivocally linked to autoimmunity only recently, with the discovery of the underlying genetic and biochemical mechanisms. The most common causal loci encode immune receptors, which are known to differ within and between species. One mechanism can be explained by the guard hypothesis, in which a guard protein, often a nucleotide-binding site-leucine-rich repeat protein, is activated by interaction with a plant protein that mimics standard guardees modified by pathogen effector proteins. Another surprising mechanism is the formation of inappropriately active immune receptor complexes. In this review, we summarize our current knowledge of hybrid necrosis and discuss how its study is not only informing the understanding of immune gene evolution but also revealing new aspects of plant immune signaling.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annual review of phytopathology
Annual review of phytopathology 生物-植物科学
CiteScore
16.60
自引率
1.00%
发文量
19
期刊介绍: The Annual Review of Phytopathology, established in 1963, covers major advancements in plant pathology, including plant disease diagnosis, pathogens, host-pathogen Interactions, epidemiology and ecology, breeding for resistance and plant disease management, and includes a special section on the development of concepts. The journal is now open access through Annual Reviews' Subscribe to Open program, with articles published under a CC BY license.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信