海洋生物多糖及其对乳腺癌的抗癌作用

IF 3.597 Q2 Pharmacology, Toxicology and Pharmaceutics

MedChemComm Pub Date : 2023-04-13 DOI:10.1039/D3MD00035D

Shengfeng Yang, Dacheng Li, Weili Liu and Xiaolin Chen

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引用次数: 0

摘要

近几十年来，海洋生物的天然产物已被广泛研究用于治疗各种乳腺癌。其中，多糖因其良好的疗效和安全性而受到研究者的青睐。本文综述了海藻中的多糖，包括大型藻类和微藻、壳聚糖、海洋细菌和真菌等微生物以及海星。详细讨论了它们对不同乳腺癌的抗癌活性及其作用机制。一般来说，来自海洋生物的多糖是开发低副作用和高效抗癌药物的潜在来源。然而，还需要进一步的动物研究和临床研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Polysaccharides from marine biological resources and their anticancer activity on breast cancer

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Polysaccharides from marine biological resources and their anticancer activity on breast cancer

In recent decades, natural products from marine organisms have been widely studied for the treatment of various breast cancers. Among them, polysaccharides have been favored by researchers because of their good effects and safety. In this review, polysaccharides from marine algae including macroalgae and microalgae, chitosan, microorganisms such as marine bacteria and fungi, and starfish are addressed. Their anticancer activities on different breast cancers and action mechanisms are discussed in detail. In general, polysaccharides from marine organisms are potential sources of low side-effect and high efficiency anticancer drugs for development. However, further research on animals and clinical research are needed.

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来源期刊

MedChemComm BIOCHEMISTRY & MOLECULAR BIOLOGY-CHEMISTRY, MEDICINAL

CiteScore

4.70

自引率

0.00%

发文量

审稿时长

2.2 months

期刊介绍： Research and review articles in medicinal chemistry and related drug discovery science; the official journal of the European Federation for Medicinal Chemistry. In 2020, MedChemComm will change its name to RSC Medicinal Chemistry. Issue 12, 2019 will be the last issue as MedChemComm.