吸烟是脊柱炎相关葡萄膜炎的相关因素:来自单中心横断面研究的结果。

IF 1 4区医学 Q4 RHEUMATOLOGY

Acta reumatologica portuguesa Pub Date : 2020-10-01

Emanuel Costa, Diogo Almeida, Marcos Cerqueira, José Redondo Costa, Ana Roxo Ribeiro, Joana Sousa-Neves

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引用次数: 0

摘要

脊柱关节炎(SpA)的眼部受累是一种常见的关节外表现，并导致疾病负担。与脊椎关节炎相关性葡萄膜炎(SpA-U)相关的因素在文献中定义不清。吸烟状况对SpA患者葡萄膜炎发生的影响尚存争议。为了阐明与SpA-U相关的因素，我们在三级风湿病中心进行了一项观察性横断面研究。通过logistic回归模型确定与葡萄膜炎独立相关的因素。该研究包括164名符合ASAS轴向SpA标准的患者，随访时间为2019年1月至6月。吸烟与葡萄膜炎独立相关(OR=2.54;95%可信区间(1.01 - -6.42);p = 0.03)。我们的研究强调了在SpA中戒烟的重要性，戒烟可能对不同的疾病特征，如葡萄膜炎和整体预后有积极的影响。

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Smoking as associated factor for spondyloarthritis related uveitis: results from a single centre cross-sectional study.

Ocular involvement in spondyloarthritis (SpA) is a frequent extra-articular manifestation and contributes to the burden of disease. Factors associated with spondyloarthritis-related uveitis (SpA-U) are poorly defined in literature. The influence of smoking status on the occurrence of uveitis in SpA is controversial. To clarify the factors associated with SpA-U, we performed an observational cross-sectional study in a Tertiary Rheumatology Centre. Factors independently associated with uveitis were determined by logistic regression models. The study included 164 patients fulfilling the ASAS criteria for axial SpA with follow-up visit between January and June 2019. Smoking was independently associated with uveitis (OR=2.54; 95%CI [1.01-6.42]; p=0.03). Our study emphasizes the importance of smoking cessation in SpA which may have a positive effect in different disease features like uveitis and overall prognosis.

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来源期刊

Acta reumatologica portuguesa 医学-风湿病学

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Acta Reumatólogica Portuguesa is a scientific peer reviewed journal covering all aspects of rheumatic diseases and related to Rheumatology. The journal publishes original articles, reviews, clinical cases, images in rheumatology, letters to the editor and clinical teaching (e.g. guidelines and clinical protocols). Published since 1973, Acta Reumatológica Portuguesa is the official scientific publication of the Portuguese Society of Rheumatology, a non-profit organization that promotes the knowledge and investigation of rheumatic diseases and the development of Rheumatology.