成功治疗介形性银屑病伴银屑病关节炎的儿童一例报告。

IF 5.2 Q1 DERMATOLOGY
Psoriasis (Auckland, N.Z.) Pub Date : 2020-12-30 eCollection Date: 2020-01-01 DOI:10.2147/PTT.S285832
Rasmia Rowawi, Gilang Dwipangestu, Oki Suwarsa, Hartati Purbo Dharmadji, Endang Sutedja, Miranti Pangastuti, Hendra Gunawan
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引用次数: 1

摘要

牛皮癣可能表现为严重的角化过度病变,类似牡蛎壳,称为介形性牛皮癣(OP)。这种类型的银屑病非常罕见,通常与银屑病关节炎(PA)有关。儿童OP合并PA的病例从未报道过。我们报告了一个9岁的女孩,她全身出现类似牡蛎壳的角化过度病变,并伴有手指、膝关节和脚踝关节肿胀。组织病理学检查支持op的诊断。根据银屑病关节炎分类标准(CASPAR)建立PA的诊断。在开始环孢素和高效局部类固醇与润肤剂联合治疗后44天内,观察到皮肤病变和关节的显著改善。OP合并PA在儿童中并不常见。强效皮质类固醇联合润肤剂对皮肤改善效果好,副作用小。此外,环孢素可以作为儿童OP合并PA的全身治疗的良好选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Successful Treatment of Ostraceous Psoriasis Associated with Psoriatic Arthritis in Children: A Case Report.

A Successful Treatment of Ostraceous Psoriasis Associated with Psoriatic Arthritis in Children: A Case Report.

A Successful Treatment of Ostraceous Psoriasis Associated with Psoriatic Arthritis in Children: A Case Report.

A Successful Treatment of Ostraceous Psoriasis Associated with Psoriatic Arthritis in Children: A Case Report.

Psoriasis may manifest as severe hyperkeratotic lesions resembling an oyster shell called ostraceous psoriasis (OP). This type of psoriasis is extremely rare and is often associated with psoriatic arthritis (PA). Cases of OP associated with PA in children have never been reported before. We reported a 9-year-old girl with hyperkeratotic lesions resembling an oyster shell all over the body accompanied with swelling on joints of both fingers, knee joints, and ankle. Histopathological examination supported the diagnosis of OP. The diagnosis of PA was established according to the Classification Criteria for Psoriatic Arthritis (CASPAR). Significant improvements of the skin lesions and joints involved were observed within 44 days after the beginning of treatment with cyclosporine and a combination of high potent topical steroid with emollient. OP associated with PA is uncommonly seen in children. High potent corticosteroid combined with emollient showed good result in skin improvement with low side effects. In addition, cyclosporine can be a good choice of systemic therapy for OP with PA in children.

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