库欣样患者伴转移性前列腺癌的低钾血症和外周水肿。

4区 医学 Q3 Medicine
Netherlands Journal of Medicine Pub Date : 2020-12-01
L M Schepers, J M H Kisters, C Wetzels, G J Creemers
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引用次数: 0

摘要

我们报告一位75岁的男性,有转移性前列腺癌病史,表现为血尿、外周水肿、代谢性碱中毒、低钾血症和高血压。实验室评估与促肾上腺皮质激素(ACTH)依赖库欣综合征的诊断一致,提示ACTH异位产生。前列腺活检标本病理显示前列腺大细胞神经内分泌癌(LCNEC)。本报告描述一例库欣综合征,可能是由前列腺LCNEC的异位ACTH分泌引起的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hypokalaemia and peripheral oedema in a Cushingoid patient with metastatic prostate cancer.

We report on a 75-year-old man with a history of metastatic prostate cancer who presented with haematuria, peripheral oedema, metabolic alkalosis, hypokalaemia, and hypertension. Laboratory evaluation was compatible with the diagnosis of adrenocorticotropic hormone (ACTH)-dependent cushing's syndrome and suggestive of ectopic ACTH production. Pathology of a prostate biopsy specimen showed a large cell neuroendocrine carcinoma (LCNEC) of the prostate. This report describes a case of Cushing's syndrome that was probably caused by ectopic ACTH secretion by a LCNEC of the prostate.

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来源期刊
Netherlands Journal of Medicine
Netherlands Journal of Medicine 医学-医学:内科
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The Netherlands Journal of Medicine publishes papers in all relevant fields of internal medicine. In addition to reports of original clinical and experimental studies, reviews on topics of interest or importance, case reports, book reviews and letters to the editor are welcomed.
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