产前暴露于子痫前期是子代长期内分泌疾病的危险因素。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2020-12-02 DOI:10.1080/10641955.2020.1854300

Sharon Davidesko, Kira Nahum Sacks, Michael Friger, Alon Haim, Eyal Sheiner

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引用次数: 5

摘要

目的:分析子痫前期作为儿童内分泌疾病的危险因素。研究设计:一项基于人群的队列分析，比较1991-2014年间出生的儿童与患有和未患有先兆子痫的母亲之间内分泌疾病的风险。结果:该研究包括253,808例分娩。暴露的后代因内分泌而住院的次数显著增加(0.7% vs 0.4%;p p p = 0.005)。结论:子痫前期是子代长期内分泌疾病的独立危险因素，尤其是肥胖。

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Prenatal exposure to preeclampsia as a risk factor for long-term endocrine morbidity of the offspring.

Objective: To analyze preeclampsia as a risk factor for pediatric endocrine disease. Study Design: A population-based cohort analysis comparing the risk of endocrine morbidity of children born between 1991-2014 to mothers with and without preeclampsia. Results: The study included 253,808 deliveries. Exposed offspring had significantly more endocrine hospitalizations (0.7% vs 0.4%; p < 0.001), specifically obesity (0.4% vs 0.2%, p < 0.001). While controlling for confounders, the exposed offspring had significantly more endocrine morbidity (OR 1.433 95% CI 1.115-1.841 p = 0.005). Conclusion: Preeclampsia is an independent risk factor for long-term endocrine disease of the offspring, specifically obesity.

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来源期刊

Hypertension in Pregnancy 医学-妇产科学

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.