JAK抑制剂治疗小儿斑秃

Q2 Medicine

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2020-11-01 DOI:10.1016/j.jisp.2020.04.005

Claire E. Hamilton , Brittany G. Craiglow

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引用次数: 12

摘要

斑秃是一种常见的自身免疫性疾病，严重影响儿童的生活质量。很少有安全有效的治疗方法可用于治疗严重影响的儿科患者。JAK抑制剂最近被证实是一种有效且耐受性良好的成人治疗方法，但关于使用JAK抑制剂治疗儿童斑秃的数据有限。在这里，我们回顾了关于在皮肤病学和其他医学学科的儿童中使用JAK抑制剂的现有文献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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JAK Inhibitors for the Treatment of Pediatric Alopecia Areata

Alopecia areata is a common autoimmune condition that disproportionately affects children and can significantly hinder quality of life. Few safe and effective therapies are available for the treatment of severely affected pediatric patients. JAK inhibitors have been recently established as an effective and well-tolerated therapy in adults, but there are limited data regarding the use of JAK inhibitors to treat alopecia areata in children. Here, we review the available literature regarding the use of JAK inhibitors in children in dermatology and across other medical disciplines.

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来源期刊

Journal of Investigative Dermatology Symposium Proceedings 医学-皮肤病学

自引率

0.00%

发文量

期刊介绍： Journal of Investigative Dermatology Symposium Proceedings (JIDSP) publishes peer-reviewed, invited papers relevant to all aspects of cutaneous biology and skin disease. Papers in the JIDSP are often initially presented at a scientific meeting. Potential topics include biochemistry, biophysics, carcinogenesis, cellular growth and regulation, clinical research, development, epidemiology and other population-based research, extracellular matrix, genetics, immunology, melanocyte biology, microbiology, molecular and cell biology, pathology, pharmacology and percutaneous absorption, photobiology, physiology, and skin structure.