Joseph D Orkin, Lukas F K Kuderna, Tomas Marques-Bonet
{"title":"灵长类动物多样性:从生物医学到保护基因组学。","authors":"Joseph D Orkin, Lukas F K Kuderna, Tomas Marques-Bonet","doi":"10.1146/annurev-animal-061220-023138","DOIUrl":null,"url":null,"abstract":"<p><p>Until now, the field of primate genomics has focused on two major themes: understanding human evolution and advancing biomedical research. We propose that it is now time for a third theme to receive attention: conservation genomics. As a result of anthropogenic effects, the majority of primate species have become threatened with extinction. A more robust primate conservation genomics will allow for genetically informed population management. Thanks to a steady decline in the cost of sequencing, it has now become feasible to sequence whole primate genomes at the population level. Furthermore, technological advances in noninvasive genomic methods have made it possible to acquire genome-scale data from noninvasive biomaterials. Here, we review recent advances in the analysis of primate diversity, with a focus on genomic data sets across the radiation.</p>","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":"9 ","pages":"103-124"},"PeriodicalIF":8.7000,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-animal-061220-023138","citationCount":"8","resultStr":"{\"title\":\"The Diversity of Primates: From Biomedicine to Conservation Genomics.\",\"authors\":\"Joseph D Orkin, Lukas F K Kuderna, Tomas Marques-Bonet\",\"doi\":\"10.1146/annurev-animal-061220-023138\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Until now, the field of primate genomics has focused on two major themes: understanding human evolution and advancing biomedical research. We propose that it is now time for a third theme to receive attention: conservation genomics. As a result of anthropogenic effects, the majority of primate species have become threatened with extinction. A more robust primate conservation genomics will allow for genetically informed population management. Thanks to a steady decline in the cost of sequencing, it has now become feasible to sequence whole primate genomes at the population level. Furthermore, technological advances in noninvasive genomic methods have made it possible to acquire genome-scale data from noninvasive biomaterials. Here, we review recent advances in the analysis of primate diversity, with a focus on genomic data sets across the radiation.</p>\",\"PeriodicalId\":48953,\"journal\":{\"name\":\"Annual Review of Animal Biosciences\",\"volume\":\"9 \",\"pages\":\"103-124\"},\"PeriodicalIF\":8.7000,\"publicationDate\":\"2021-02-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1146/annurev-animal-061220-023138\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annual Review of Animal Biosciences\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1146/annurev-animal-061220-023138\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/11/16 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual Review of Animal Biosciences","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1146/annurev-animal-061220-023138","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/11/16 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
The Diversity of Primates: From Biomedicine to Conservation Genomics.
Until now, the field of primate genomics has focused on two major themes: understanding human evolution and advancing biomedical research. We propose that it is now time for a third theme to receive attention: conservation genomics. As a result of anthropogenic effects, the majority of primate species have become threatened with extinction. A more robust primate conservation genomics will allow for genetically informed population management. Thanks to a steady decline in the cost of sequencing, it has now become feasible to sequence whole primate genomes at the population level. Furthermore, technological advances in noninvasive genomic methods have made it possible to acquire genome-scale data from noninvasive biomaterials. Here, we review recent advances in the analysis of primate diversity, with a focus on genomic data sets across the radiation.
期刊介绍:
The Annual Review of Animal Biosciences is primarily dedicated to the fields of biotechnology, genetics, genomics, and breeding, with a special focus on veterinary medicine. This includes veterinary pathobiology, infectious diseases and vaccine development, and conservation and zoo biology. The publication aims to address the needs of scientists studying both wild and domesticated animal species, veterinarians, conservation biologists, and geneticists.