基于新一代测序的临床宏基因组学在糖尿病青少年中发现了大量肺旁积液和胸膜液培养阴性生长的胸膜炎普雷沃氏菌:一个病例报告。

IF 2.7 4区医学 Q2 MEDICAL LABORATORY TECHNOLOGY

British Journal of Biomedical Science Pub Date : 2021-04-01 Epub Date: 2021-01-13 DOI:10.1080/09674845.2020.1827846

T Galliguez, P Y Tsou, A Cabrera, J Fergie

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引用次数: 4

摘要

我们报告一个12岁的糖尿病男孩与右侧肺旁积液和肺炎谁失败的初始经验性抗生素。采用基于新一代测序的临床元基因组学方法从胸膜液中鉴定出胸膜炎普雷沃氏菌，胸膜液和血液培养结果为阴性。患者静脉注射美罗培南后口服甲硝唑反应良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Next-generation sequencing-based clinical metagenomics identifies Prevotella pleuritidis in a diabetic adolescent with large parapneumonic effusion and negative growth of pleural fluid culture: a case report.

We report a 12-year-old diabetic boy with a right-sided parapneumonic effusion and pneumonia who failed initial empirical antibiotics. Prevotella pleuritidis was identified from the pleural fluid using next-generation sequencing-based clinical metagenomics with cultures of pleural fluid and blood resulting negative. The patient responded well to intravenous meropenem followed by oral metronidazole.

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来源期刊

British Journal of Biomedical Science 医学-医学实验技术

CiteScore

4.40

自引率

15.80%

发文量

审稿时长

>12 weeks

期刊介绍： The British Journal of Biomedical Science is committed to publishing high quality original research that represents a clear advance in the practice of biomedical science, and reviews that summarise recent advances in the field of biomedical science. The overall aim of the Journal is to provide a platform for the dissemination of new and innovative information on the diagnosis and management of disease that is valuable to the practicing laboratory scientist.