一例7个月大女婴巨细胞病毒感染继发的婴儿肾病综合征:更昔洛韦治疗

IF 1.4 4区医学 Q3 PEDIATRICS

Paediatrics and International Child Health Pub Date : 2021-05-01 Epub Date: 2020-09-29 DOI:10.1080/20469047.2020.1823176

Jasleen Kaur, Bobbity Deepthi, Rachita Singh Dhull, M D Faruq, Abhijeet Saha

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引用次数: 0

摘要

婴儿肾病综合征是一种罕见的疾病，通常是由遗传缺陷引起的。一个7个月大的女孩表现为发烧，稀便和无血，并被诊断为肾病综合征。基因检查结果为阴性。巨细胞病毒聚合酶链反应(CMV PCR)阳性，患儿给予更昔洛韦治疗6周，随后给予缬更昔洛韦治疗10周。所有症状在开始治疗2周内消失，4周内完全缓解。抗病毒治疗4周内CMV PCR为阴性。在18个月的随访中，她保持良好。对继发于巨细胞病毒的婴儿肾病综合征进行适当的治疗应能使其康复。

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Infantile nephrotic syndrome secondary to cytomegalovirus infection in a 7-month-old girl: resolution with ganciclovir.

Infantile nephrotic syndrome is a rare disorder which is frequently caused by genetic defects. A 7-month-old girl presented with fever, loose stools and anasarca and was diagnosed with nephrotic syndrome. Work-up for a genetic cause was negative. Cytomegalovirus polymerase chain reaction (CMV PCR) was positive and the infant was treated with ganciclovir for 6 weeks, followed by valganciclovir for 10 weeks. All symptoms resolved within 2 weeks of commencing treatment and she attained complete remission within 4 weeks. CMV PCR was negative within 4 weeks of antiviral therapy. At 18 months follow-up she remained well. Appropriate treatment of infantile nephrotic syndrome secondary to CMV should result in recovery.

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来源期刊

Paediatrics and International Child Health PEDIATRICS-

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Paediatrics and International Child Health is an international forum for all aspects of paediatrics and child health in developing and low-income countries. The international, peer-reviewed papers cover a wide range of diseases in childhood and examine the social and cultural settings in which they occur. Although the main aim is to enable authors in developing and low-income countries to publish internationally, it also accepts relevant papers from industrialised countries. The journal is a key publication for all with an interest in paediatric health in low-resource settings.