Nidia Castro Dos Santos, Cassia Fernandes Araujo, Naira Maria Rebelatto Bechara Andere, Manuela Maria Viana Miguel, Miriam Raquel Ardigo Westphal, Thomas Van Dyke, Mauro Pedrine Santamaria
{"title":"Omega-3脂肪酸和低剂量阿司匹林治疗牙周炎和代谢综合征:病例报告。","authors":"Nidia Castro Dos Santos, Cassia Fernandes Araujo, Naira Maria Rebelatto Bechara Andere, Manuela Maria Viana Miguel, Miriam Raquel Ardigo Westphal, Thomas Van Dyke, Mauro Pedrine Santamaria","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome.</p><p><strong>Methods: </strong>Periodontal and systemic parameters were assessed at baseline and 6 months. Gingival crevicular fluid was analyzed for interleukin (IL)-1β, IL-6 and interferon (IFN)-γ levels by multiplex ELISA at baseline, 3 and 6 months.</p><p><strong>Results: </strong>The treatment was effective in reducing probing depth, clinical attachment level, bleeding on probing and plaque index, and glycated hemoglobin, triglycerides IL-1β, IL-6 and IFN-γ levels over time.</p><p><strong>Conclusions: </strong>The adjunctive use of ω-3 and low-dose aspirin to periodontal debridement might have potential benefits in the treatment of periodontitis in a patient with metabolic syndrome.</p>","PeriodicalId":17281,"journal":{"name":"Journal of the International Academy of Periodontology","volume":"22 4","pages":"223-230"},"PeriodicalIF":0.0000,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Omega-3 Fatty Acids and Low-Dose Aspirin in the Treatment of Periodontitis and Metabolic Syndrome: Case Report.\",\"authors\":\"Nidia Castro Dos Santos, Cassia Fernandes Araujo, Naira Maria Rebelatto Bechara Andere, Manuela Maria Viana Miguel, Miriam Raquel Ardigo Westphal, Thomas Van Dyke, Mauro Pedrine Santamaria\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome.</p><p><strong>Methods: </strong>Periodontal and systemic parameters were assessed at baseline and 6 months. Gingival crevicular fluid was analyzed for interleukin (IL)-1β, IL-6 and interferon (IFN)-γ levels by multiplex ELISA at baseline, 3 and 6 months.</p><p><strong>Results: </strong>The treatment was effective in reducing probing depth, clinical attachment level, bleeding on probing and plaque index, and glycated hemoglobin, triglycerides IL-1β, IL-6 and IFN-γ levels over time.</p><p><strong>Conclusions: </strong>The adjunctive use of ω-3 and low-dose aspirin to periodontal debridement might have potential benefits in the treatment of periodontitis in a patient with metabolic syndrome.</p>\",\"PeriodicalId\":17281,\"journal\":{\"name\":\"Journal of the International Academy of Periodontology\",\"volume\":\"22 4\",\"pages\":\"223-230\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the International Academy of Periodontology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the International Academy of Periodontology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Omega-3 Fatty Acids and Low-Dose Aspirin in the Treatment of Periodontitis and Metabolic Syndrome: Case Report.
Aims: To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome.
Methods: Periodontal and systemic parameters were assessed at baseline and 6 months. Gingival crevicular fluid was analyzed for interleukin (IL)-1β, IL-6 and interferon (IFN)-γ levels by multiplex ELISA at baseline, 3 and 6 months.
Results: The treatment was effective in reducing probing depth, clinical attachment level, bleeding on probing and plaque index, and glycated hemoglobin, triglycerides IL-1β, IL-6 and IFN-γ levels over time.
Conclusions: The adjunctive use of ω-3 and low-dose aspirin to periodontal debridement might have potential benefits in the treatment of periodontitis in a patient with metabolic syndrome.