特洛伊·d·扎尔斯(1967-2018)的传记小品。

IF 1.8 4区医学 Q3 GENETICS & HEREDITY

Journal of neurogenetics Pub Date : 2020-03-01 DOI:10.1080/01677063.2020.1716749

Bertram Gerber, Elizabeth G King, Divya Sitaraman

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引用次数: 0

摘要

特洛伊·扎尔斯(Troy D. Zars, 1967-2018)，美国生物学家。他研究了黑腹果蝇的基因、神经回路和行为之间的关系。Zars共同开创了使用转基因表达来局部恢复记忆缺陷果蝇突变体的基因功能的方法，这种方法为果蝇大脑中记忆痕迹的定位提供了突破性的见解。随着随后转基因表达方法的改进和转基因表达范围的扩大，这形成了现代行为神经遗传学领域。

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A biographical sketch of Troy D. Zars (1967-2018).

Troy D. Zars (1967-2018) was an American biologist. He studied the relationships between genes, neuronal circuits and behavior in the fruit fly Drosophila melanogaster. Zars co-pioneered the use of transgene expression to locally restore gene function in memory-defective fly mutants, an approach that provided breakthrough insights into the localization of memory traces in the fly brain. With ensuing refinements of the methods of transgene expression and the broadening in the range of transgenes to be expressed, this shaped the field of modern behavioral neurogenetics.

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来源期刊

Journal of neurogenetics 医学-神经科学

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal is appropriate for papers on behavioral, biochemical, or cellular aspects of neural function, plasticity, aging or disease. In addition to analyses in the traditional genetic-model organisms, C. elegans, Drosophila, mouse and the zebrafish, the Journal encourages submission of neurogenetic investigations performed in organisms not easily amenable to experimental genetics. Such investigations might, for instance, describe behavioral differences deriving from genetic variation within a species, or report human disease studies that provide exceptional insights into biological mechanisms