殖民地刺胞动物水螅。

IF 4.1 2区 生物学 Q1 DEVELOPMENTAL BIOLOGY
Evodevo Pub Date : 2020-03-26 eCollection Date: 2020-01-01 DOI:10.1186/s13227-020-00151-0
Uri Frank, Matthew L Nicotra, Christine E Schnitzler
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引用次数: 25

摘要

水螅虫是一种殖民地海洋刺胞动物属,一个多世纪以来一直被用作发育生物学和比较免疫学的模式生物。干细胞和生殖细胞就是在这种动物身上首次被研究的。然而,高效基因工程的协议直到最近才由一个小而互动的研究团体建立起来。这种动物在实验室里生长良好,每天产卵,其相对较短的生命周期允许进行基因研究。基因组工具和资源的可用性为利用这种动物进行研究提供了进一步的机会。它易于实验操作、生长和细胞可塑性、再生能力、抗衰老和抗癌性使水葫芦成为许多生物和环境学科研究的新兴模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The colonial cnidarian <i>Hydractinia</i>.

The colonial cnidarian <i>Hydractinia</i>.

The colonial cnidarian <i>Hydractinia</i>.

The colonial cnidarian Hydractinia.

Hydractinia, a genus of colonial marine cnidarians, has been used as a model organism for developmental biology and comparative immunology for over a century. It was this animal where stem cells and germ cells were first studied. However, protocols for efficient genetic engineering have only recently been established by a small but interactive community of researchers. The animal grows well in the lab, spawns daily, and its relatively short life cycle allows genetic studies. The availability of genomic tools and resources opens further opportunities for research using this animal. Its accessibility to experimental manipulation, growth- and cellular-plasticity, regenerative ability, and resistance to aging and cancer place Hydractinia as an emerging model for research in many biological and environmental disciplines.

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来源期刊
Evodevo
Evodevo EVOLUTIONARY BIOLOGY-DEVELOPMENTAL BIOLOGY
CiteScore
7.50
自引率
0.00%
发文量
18
审稿时长
>12 weeks
期刊介绍: EvoDevo publishes articles on a broad range of topics associated with the translation of genotype to phenotype in a phylogenetic context. Understanding the history of life, the evolution of novelty and the generation of form, whether through embryogenesis, budding, or regeneration are amongst the greatest challenges in biology. We support the understanding of these processes through the many complementary approaches that characterize the field of evo-devo. The focus of the journal is on research that promotes understanding of the pattern and process of morphological evolution. All articles that fulfill this aim will be welcome, in particular: evolution of pattern; formation comparative gene function/expression; life history evolution; homology and character evolution; comparative genomics; phylogenetics and palaeontology
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