不适当抗利尿综合征继发的低钠血症。

2区医学 Q2 Medicine

Frontiers of Hormone Research Pub Date : 2019-01-01 Epub Date: 2019-01-15 DOI:10.1159/000493238

Joseph G Verbalis

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引用次数: 19

摘要

低血容量性低钠血症是住院患者和门诊患者低钠血症的最常见原因。低钠血症最常见的病因是不适当抗利尿综合征(SIAD)。SIAD的诊断需要对一套长期存在的临床和实验室诊断标准进行评估。SIAD有许多治疗方案，在其中的选择应基于低钠血症的慢性性和神经症状。重要的是，针对特定患者的个体化临床判断和风险/收益分析应该推动治疗决策，因为没有一种治疗方法代表所有SIAD患者的“最佳”治疗。

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Euvolemic Hyponatremia Secondary to the Syndrome of Inappropriate Antidiuresis.

Euvolemic hyponatremia is the most common cause of hyponatremia in both hospitalized patients and outpatients. The most common etiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Diagnosis of SIAD involves evaluation of a set of long-standing clinical and laboratory criteria for this diagnosis. Many treatment options for SIAD exist, and choosing among them should be based on the chronicity of the hyponatremia and neurological symptomatology. Importantly, clinical judgment and risk/benefit analysis that is individualized for specific patients should drive therapeutic decisions, because there is no single treatment that represents the "best" therapy for all patients with SIAD.

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来源期刊

Frontiers of Hormone Research 医学-内分泌学与代谢

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期刊介绍： A series of integrated overviews on cutting-edge topics New sophisticated technologies and methodological approaches in diagnostics and therapeutics have led to significant improvements in identifying and characterizing an increasing number of medical conditions, which is particularly true for all aspects of endocrine and metabolic dysfunctions. Novel insights in endocrine physiology and pathophysiology allow for new perspectives in clinical management and thus lead to the development of molecular, personalized treatments. In view of this, the active interplay between basic scientists and clinicians has become fundamental, both to provide patients with the most appropriate care and to advance future research.