Studying neural circuits of decision-making in Drosophila larva.

To study neural circuits underlying decisions, the model organism used for that purpose has to be simple enough to be able to dissect the circuitry neuron by neuron across the nervous system and in the same time complex enough to be able to perform different types of decisions. Here, I lay out the case: (1) that Drosophila larva is an advantageous model system that balances well these two requirements and (2) the insights gained from this model, assuming that circuit principles may be shared across species, can be used to advance our knowledge of neural circuit implementation of decision-making in general, including in more complex brains.