探索特发性颅内高压症的治疗现状,了解硬脑膜静脉窦支架植入术的作用。

IF 3.1 Q1 OPHTHALMOLOGY
Eye and Brain Pub Date : 2020-01-14 eCollection Date: 2020-01-01 DOI:10.2147/EB.S193027
Sam P Gurney, Sateesh Ramalingam, Alan Thomas, Alex J Sinclair, Susan P Mollan
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引用次数: 0

摘要

特发性颅内高压症(IIH)是一种使人衰弱的疾病,其特征是颅内压(ICP)升高、乳头水肿(有永久性视力丧失的潜在风险)以及严重致残和降低生活质量的头痛。关于成人 IIH 的检查和管理的第一份共识指南已经发布,其中一个关键的不确定因素是硬脑膜静脉窦支架植入术在治疗头痛和视力丧失方面的效用。发表的系列文章越来越多,有助于了解成功案例和并发症。在确定患者和医生优先考虑的问题时,了解治疗 IIH 的最佳干预方式被列为该疾病最需要研究的前 10 个问题。神经血管支架置入术治疗 IIH 的随机临床试验(RCT)最终将具有指导意义,因为迄今为止的文献可能存在发表偏差。由于 IIH 的发病率越来越高,现在是系统研究可逆转疾病进程并实现缓解的干预措施的最佳时机。在这篇综述中,我们将讨论 IIH 的病理生理学与静脉窦狭窄的关系、静脉窦支架置入术的作用及相关文献综述、支架置入术与其他外科干预措施相比的优缺点以及支架置入术在 IIH 治疗中的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring The Current Management Idiopathic Intracranial Hypertension, And Understanding The Role Of Dural Venous Sinus Stenting.

Idiopathic Intracranial Hypertension (IIH) is a debilitating disorder characterised by raised intracranial pressure (ICP), papilloedema with the potential risk of permanent visual loss, and headaches that are profoundly disabling and reduce the quality of life. The first consensus guidelines have been published on investigation and management of adult IIH and one key area of uncertainty is the utility of dural venous sinus stenting for the management of headache and visual loss. There are an increasing number of series published and to help understand the successes and complications. During a patient physician priority setting, the understanding of the best type of intervention to treat IIH was assigned to the top 10 of most desired research questions for the disease. Ultimately randomised clinical trials (RCTs) in neurovascular stenting for IIH would be instructive, as the literature to date may suffer from publication bias. Due to the increasing incidence of IIH, there is no better time to systematically investigate interventions that may reverse the disease process and achieve remission. In this review we discuss the pathophysiology of IIH in relation to venous sinus stenosis, the role of venous sinus stenting with a review of the relevant literature, the advantages and disadvantages of stenting compared with other surgical interventions, and the future of stenting in the treatment of IIH.

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来源期刊
Eye and Brain
Eye and Brain OPHTHALMOLOGY-
CiteScore
7.90
自引率
2.30%
发文量
12
审稿时长
16 weeks
期刊介绍: Eye and Brain is an international, peer-reviewed, open access journal focusing on basic research, clinical findings, and expert reviews in the field of visual science and neuro-ophthalmology. The journal’s unique focus is the link between two well-known visual centres, the eye and the brain, with an emphasis on the importance of such connections. All aspects of clinical and especially basic research on the visual system are addressed within the journal as well as significant future directions in vision research and therapeutic measures. This unique journal focuses on neurological aspects of vision – both physiological and pathological. The scope of the journal spans from the cornea to the associational visual cortex and all the visual centers in between. Topics range from basic biological mechanisms to therapeutic treatment, from simple organisms to humans, and utilizing techniques from molecular biology to behavior. The journal especially welcomes primary research articles or review papers that make the connection between the eye and the brain. Specific areas covered in the journal include: Physiology and pathophysiology of visual centers, Eye movement disorders and strabismus, Cellular, biochemical, and molecular features of the visual system, Structural and functional organization of the eye and of the visual cortex, Metabolic demands of the visual system, Diseases and disorders with neuro-ophthalmic manifestations, Clinical and experimental neuro-ophthalmology and visual system pathologies, Epidemiological studies.
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