阿片类药物处方行为-处方行为监测系统,11个州,2010-2016。

IF 37.3 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Gail K Strickler, Peter W Kreiner, John F Halpin, Erin Doyle, Leonard J Paulozzi
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引用次数: 56

摘要

问题/状况:2017年,美国共有70,237人死于药物过量,其中67.8%的死亡与阿片类药物有关。从历史上看,美国的阿片类药物过量流行与阿片类药物处方的平行增加和这些药物的广泛滥用密切相关。自2010年以来,国家和州决策者采取了多种措施,试图评估和控制阿片类药物过量的流行,包括改进监测系统。系统描述:处方行为监测系统(PBSS)于2011年创建。它的目标是利用选定的州处方药监测项目(PDMP)的数据,跟踪管制药物的处方率和可能滥用此类药物的情况。PBSS数据使用PDMP数据计算的多个指标衡量处方阿片类药物的处方行为,包括1)阿片类药物处方,2)阿片类药物平均每日剂量,3)阿片类药物每日剂量≥90吗啡毫克当量的患者比例,4)阿片类药物处方重叠,5)阿片类药物和苯二氮卓类药物处方重叠,6)多提供者事件。在这项分析中,PBSS数据来自2010-2016年11个州,约占美国人口的38.0%:计算每个州阿片类药物处方率和可能的阿片类药物滥用措施的平均季度百分比变化(AQPC)。结果和解释:2010-2016年,所有11个州的阿片类药物处方率都有所下降(范围:14.9%至33.0%)。爱达荷州和缅因州的日剂量降幅最小(AQPC: -0.4%),佛罗里达州降幅最大(AQPC: -1.6%)。高日剂量患者AQPCs百分比从爱达荷州的-0.4%到路易斯安那州的-2.3%不等。在七个有数据可查的州,多家医院的发生率至少下降了62%。11个州趋势的变化可能反映了各州政策的差异,以及类似政策可能产生的不同效果。公共卫生行动:与使用国家可获得的商业处方数据相比,使用来自各州的PDMP数据能够更详细地审查阿片类药物处方行为的趋势和可能的滥用指标。对各州阿片类药物处方趋势的比较可用于监测国家或州政策干预措施的时间相关性,并可能有助于公共卫生政策制定者认识到受管制处方药使用或可能滥用的变化,并允许通过修订或新的阿片类药物相关政策进行及时干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Opioid Prescribing Behaviors - Prescription Behavior Surveillance System, 11 States, 2010-2016.

Opioid Prescribing Behaviors - Prescription Behavior Surveillance System, 11 States, 2010-2016.

Opioid Prescribing Behaviors - Prescription Behavior Surveillance System, 11 States, 2010-2016.

Opioid Prescribing Behaviors - Prescription Behavior Surveillance System, 11 States, 2010-2016.

Problem/condition: In 2017, a total of 70,237 persons in the United States died from a drug overdose, and 67.8% of these deaths involved an opioid. Historically, the opioid overdose epidemic in the United States has been closely associated with a parallel increase in opioid prescribing and with widespread misuse of these medications. National and state policy makers have introduced multiple measures to attempt to assess and control the opioid overdose epidemic since 2010, including improvements in surveillance systems.

Period covered: 2010-2016 DESCRIPTION OF SYSTEM: The Prescription Behavior Surveillance System (PBSS) was created in 2011. Its goal was to track rates of prescribing of controlled substances and possible misuse of such drugs using data from selected state prescription drug monitoring programs (PDMP). PBSS data measure prescribing behaviors for prescription opioids using multiple measures calculated from PDMP data including 1) opioid prescribing, 2) average daily opioid dosage, 3) proportion of patients with daily opioid dosages ≥90 morphine milligram equivalents, 4) overlapping opioid prescriptions, 5) overlapping opioid and benzodiazepine prescriptions, and 6) multiple-provider episodes. For this analysis, PBSS data were available for 2010-2016 from 11 states representing approximately 38.0% of the U.S.

Population: Average quarterly percent changes (AQPC) in the rates of opioid prescribing and possible opioid misuse measures were calculated for each state.

Results and interpretation: Opioid prescribing rates declined in all 11 states during 2010-2016 (range: 14.9% to 33.0%). Daily dosage declined least (AQPC: -0.4%) in Idaho and Maine, and most (AQPC: -1.6%) in Florida. The percentage of patients with high daily dosage had AQPCs ranging from -0.4% in Idaho to -2.3% in Louisiana. Multiple-provider episode rates declined by at least 62% in the seven states with available data. Variations in trends across the 11 states might reflect differences in state policies and possible differential effects of similar policies.

Public health actions: Use of PDMP data from individual states enables a more detailed examination of trends in opioid prescribing behaviors and indicators of possible misuse than is feasible with national commercially available prescription data. Comparison of opioid prescribing trends among states can be used to monitor the temporal association of national or state policy interventions and might help public health policymakers recognize changes in the use or possible misuse of controlled prescription drugs over time and allow for prompt intervention through amended or new opioid-related policies.

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来源期刊
Mmwr Surveillance Summaries
Mmwr Surveillance Summaries PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
60.50
自引率
1.20%
发文量
9
期刊介绍: The Morbidity and Mortality Weekly Report (MMWR) Series, produced by the Centers for Disease Control and Prevention (CDC), is commonly referred to as "the voice of CDC." Serving as the primary outlet for timely, reliable, authoritative, accurate, objective, and practical public health information and recommendations, the MMWR is a crucial publication. Its readership primarily includes physicians, nurses, public health practitioners, epidemiologists, scientists, researchers, educators, and laboratorians.
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