果蝇记忆印迹的纳米定位研究。

IF 1.8 4区医学 Q3 GENETICS & HEREDITY

Journal of neurogenetics Pub Date : 2020-03-01 Epub Date: 2020-01-27 DOI:10.1080/01677063.2020.1715973

Yoshinori Aso, Gerald M Rubin

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引用次数: 7

摘要

蘑菇体(MB)是果蝇大脑中储存联想记忆的主要位置。我们讨论了利用先进的光学显微镜方法和细胞类型特异性遗传工具来理解MB神经元回路的最新进展。我们还回顾了MB组织的分区性质如何使该大脑区域形成和存储具有广泛不同动态的记忆。

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Toward nanoscale localization of memory engrams in Drosophila.

The Mushroom Body (MB) is the primary location of stored associative memories in the Drosophila brain. We discuss recent advances in understanding the MB's neuronal circuits made using advanced light microscopic methods and cell-type-specific genetic tools. We also review how the compartmentalized nature of the MB's organization allows this brain area to form and store memories with widely different dynamics.

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来源期刊

Journal of neurogenetics 医学-神经科学

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal is appropriate for papers on behavioral, biochemical, or cellular aspects of neural function, plasticity, aging or disease. In addition to analyses in the traditional genetic-model organisms, C. elegans, Drosophila, mouse and the zebrafish, the Journal encourages submission of neurogenetic investigations performed in organisms not easily amenable to experimental genetics. Such investigations might, for instance, describe behavioral differences deriving from genetic variation within a species, or report human disease studies that provide exceptional insights into biological mechanisms