急性右心衰:PERKAT RV脉冲右心室支持装置的未来前景。

IF 2.6 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Markus W Ferrari, P Christian Schulze, Daniel Kretzschmar
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引用次数: 8

摘要

急性右心衰与心源性休克的预后受损有关。由于大多数药物治疗都没有对衰竭的右心室进行评估,甚至有禁忌症,因此需要快速微创右心循环支持。PERKAT RV就是这样一种用于充血性心力衰竭急性治疗的设备。它通过将血液从下腔静脉泵入肺动脉,以高达4升/分钟的流速减少中央静脉淤积。经过仔细的体外试验,该装置在急性肺栓塞动物模型中进行了评估。PERKAT RV使急性右心衰绵羊的心输出量增加59%。我们等待着在不久的将来进行第一次人体移植。基于PERKAT的概念,未来的发展也将集中在左心支持上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device.

Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device.

Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device.

Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device.

Acute right heart failure is associated with impaired prognosis in cardiogenic shock. Since most pharmacological therapies are not evaluated for the failing right ventricle, or even contraindicated, there is a need for rapid minimal invasive circulatory right heart support. The PERKAT RV is such a device for acute therapy in congestive heart failure. It reduces the central venous pooling by pumping blood from the inferior vena cava into the pulmonary artery with flow rates of up to 4 litres/min. The device was evaluated in an animal model of acute pulmonary embolism after careful in vitro tests. PERKAT RV increased cardiac output by 59% in sheep suffering from acute right heart failure. We await the first human implantation in the near future. Based on the PERKAT concept, future devolvement will also focus on left heart support.

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来源期刊
Therapeutic Advances in Cardiovascular Disease
Therapeutic Advances in Cardiovascular Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.50
自引率
0.00%
发文量
11
审稿时长
9 weeks
期刊介绍: The journal is aimed at clinicians and researchers from the cardiovascular disease field and will be a forum for all views and reviews relating to this discipline.Topics covered will include: ·arteriosclerosis ·cardiomyopathies ·coronary artery disease ·diabetes ·heart failure ·hypertension ·metabolic syndrome ·obesity ·peripheral arterial disease ·stroke ·arrhythmias ·genetics
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