白癜风患者血清镁浓度。

IF 1.5 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Magnesium research Pub Date : 2019-05-01 DOI:10.1684/mrh.2019.0450

M R Namazi, Farnoosh Nozari, Peyman Jafari

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引用次数: 0

摘要

低镁血症已被证明会导致氧化应激和炎症。本研究旨在评估白癜风患者与对照组的血清镁(Mg)浓度。27名白癜风患者参加了这项研究，同时还有27名年龄和性别匹配的健康对照。病例组和对照组血清Mg平均浓度分别为0.75±0.07和0.77±0.07 mmol/L。两组间Mg平均浓度差异无统计学意义(P = 0.95)。然而，有趣的是，我们注意到血清Mg浓度与白癜风区域严重程度指数(VASI)评分以及与该疾病相关的全身表面积(TBSA)呈正相关。因此，有必要进一步研究镁在白癜风中的作用。

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Serum magnesium concentrations in vitiligo patients.

Hypomagnesemia has been shown to contribute to oxidative stress and inflammation. This study was designed to evaluate the serum magnesium (Mg) concentration in vitiligo patients versus controls. Twenty-seven patients with vitiligo were enrolled in this study, along with 27 age and sex-matched healthy controls. The mean serum Mg concentrations in the case and control groups were 0.75 ± 0.07 and 0.77 ± 0.07 mmol/L, respectively. No significant difference in the mean concentrations of Mg between the two groups was noted (P = 0.95). However, interestingly, we noticed a positive correlation between serum Mg concentration and Vitiligo Area Severity Index (VASI) score as well as the total body surface area (TBSA) concerned by the disease. Further research on the role of Mg in vitiligo is therefore warranted.

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来源期刊

Magnesium research 医学-内分泌学与代谢

CiteScore

3.50

自引率

9.40%

发文量

审稿时长

>12 weeks

期刊介绍： Magnesium Research, the official journal of the international Society for the Development of Research on Magnesium (SDRM), has been the benchmark journal on the use of magnesium in biomedicine for more than 30 years. This quarterly publication provides regular updates on multinational and multidisciplinary research into magnesium, bringing together original experimental and clinical articles, correspondence, Letters to the Editor, comments on latest news, general features, summaries of relevant articles from other journals, and reports and statements from national and international conferences and symposiums. Indexed in the leading medical databases, Magnesium Research is an essential journal for specialists and general practitioners, for basic and clinical researchers, for practising doctors and academics.