Otis M Vrielink, Schelto Kruijff, Barbara L van Leeuwen, Jan Ln Roodenburg
{"title":"CO2激光蒸发在局部晚期黑色素瘤中的应用。","authors":"Otis M Vrielink, Schelto Kruijff, Barbara L van Leeuwen, Jan Ln Roodenburg","doi":"10.2217/mmt-2018-0008","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study aims to investigate the role of CO<sub>2</sub> laser evaporation in the treatment of melanoma patients with satellite or in-transit metastases.</p><p><strong>Materials & methods: </strong>Patients who underwent CO<sub>2</sub> laser evaporation were retrospectively included between November 2002 and August 2018. The Sharplan 40C CO<sub>2</sub> laser was used with a high pulse wave mode. Data concerning patient and tumor characteristics, CO<sub>2</sub> laser evaporation and subsequent therapies were collected.</p><p><strong>Results: </strong>A total of 26 patients were included. Median duration of local control was 5.5 months. The median number of lesions evaporated per treatment was three (1-16); patients received a median of three (1-19) treatments.</p><p><strong>Conclusion: </strong>In a selected group of melanoma patients with satellite or in-transit metastases, CO<sub>2</sub> laser evaporation should be considered as treatment for local control.</p>","PeriodicalId":44562,"journal":{"name":"Melanoma Management","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2019-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/mmt-2018-0008","citationCount":"1","resultStr":"{\"title\":\"Application of CO<sub>2</sub> laser evaporation in locally advanced melanoma.\",\"authors\":\"Otis M Vrielink, Schelto Kruijff, Barbara L van Leeuwen, Jan Ln Roodenburg\",\"doi\":\"10.2217/mmt-2018-0008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>This study aims to investigate the role of CO<sub>2</sub> laser evaporation in the treatment of melanoma patients with satellite or in-transit metastases.</p><p><strong>Materials & methods: </strong>Patients who underwent CO<sub>2</sub> laser evaporation were retrospectively included between November 2002 and August 2018. The Sharplan 40C CO<sub>2</sub> laser was used with a high pulse wave mode. Data concerning patient and tumor characteristics, CO<sub>2</sub> laser evaporation and subsequent therapies were collected.</p><p><strong>Results: </strong>A total of 26 patients were included. Median duration of local control was 5.5 months. The median number of lesions evaporated per treatment was three (1-16); patients received a median of three (1-19) treatments.</p><p><strong>Conclusion: </strong>In a selected group of melanoma patients with satellite or in-transit metastases, CO<sub>2</sub> laser evaporation should be considered as treatment for local control.</p>\",\"PeriodicalId\":44562,\"journal\":{\"name\":\"Melanoma Management\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2019-04-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2217/mmt-2018-0008\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Melanoma Management\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2217/mmt-2018-0008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/3/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Melanoma Management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/mmt-2018-0008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/3/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
Application of CO2 laser evaporation in locally advanced melanoma.
Aim: This study aims to investigate the role of CO2 laser evaporation in the treatment of melanoma patients with satellite or in-transit metastases.
Materials & methods: Patients who underwent CO2 laser evaporation were retrospectively included between November 2002 and August 2018. The Sharplan 40C CO2 laser was used with a high pulse wave mode. Data concerning patient and tumor characteristics, CO2 laser evaporation and subsequent therapies were collected.
Results: A total of 26 patients were included. Median duration of local control was 5.5 months. The median number of lesions evaporated per treatment was three (1-16); patients received a median of three (1-19) treatments.
Conclusion: In a selected group of melanoma patients with satellite or in-transit metastases, CO2 laser evaporation should be considered as treatment for local control.
期刊介绍：
Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.
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