Muhammad Abdul Mabood Khalil, Muhammad Shahab Ud Din Khalil, Said Sayed Ahmed Khamis, Sartaj Alam, Rajendra Govindrao Daiwajna, Ahmed Suleman Rajput, Mohammed M Alhaji, Vui Heng Chong, Jackson Tan
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Pros and Cons of Aspirin Prophylaxis for Prevention of Cardiovascular Events in Kidney Transplantation and Review of Evidence.
Kidney transplant recipients have traditional and nontraditional risk factors which can lead to coronary artery disease and sudden death with a functional graft loss. Aspirin has been used traditionally for prevention of cardiovascular and cerebrovascular accidents. It has beneficial effects in secondary prevention of cardiovascular events in general population. Its use for primary prophylaxis is still disputed. Bleeding and theoretical risk of nephrotoxicity are the major concerns about its use. The data on aspirin in kidney transplant population is sparse. This review will focus on various pros and cons of aspirin use for prevention of cardiovascular events in kidney transplant recipients and a way forward.
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