纳米悬浮液技术:药物递送及其表征的最新专利。

Q3 Pharmacology, Toxicology and Pharmaceutics
Surya Goel, Monika Sachdeva, Vijay Agarwal
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引用次数: 0

摘要

背景:纳米悬浮液是一种有报酬、利润丰厚的有效方法,可以提高水溶性差的药物的溶解度和生物利用度。这种方法仍然存在一些挑战,需要更多的研究。这项审查的主要目的是确定这些挑战,这些挑战可以在未来得到纠正。方法:通过这篇综述,我们对利用不同药物部分、仪器和表征参数的纳米混悬剂技术的最新专利和进展进行了启示。结果:纳米混悬剂被发现具有巨大的潜力,可以纠正与生物利用度差、位点特异性给药、给药频率等有关的几个问题。在过去的十年里,纳米混悬液方法被互补地用于解决因难溶性药物而产生的不满。但这个领域仍然需要更多的关注新发现。结论:纳米混悬液在通过口服、透皮、眼部、胃肠外、肺部等多种途径给药不同药物实体方面发挥着至关重要的作用,解决了不同的问题。这篇综述还证实了纳米混悬剂在安全性、疗效、公共性以及与医疗保健相关的经济费用方面的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanosuspension Technology: Recent Patents on Drug Delivery and their Characterizations.

Background: Nanosuspension has arisen as a remunerative, lucrative as well as a potent approach to improve the solubility and bioavailability of poorly aqueous soluble drug entities. Several challenges are still present in this approach which need more research. The prime aim of this review is to identify such challenges that can be rectified in the future.

Methods: Through this review, we enlighten the recent patents and advancement in nanosuspension technology that utilize the different drug moieties, instruments and characterization parameters.

Results: Nanosuspension has been found to possess great potential to rectify the several issues related to poor bioavailability, site-specific drug delivery, dosing frequency, etc. In the past decade, nanosuspension approach has been complementarily utilized to solve the developed grievances, arisen from poorly soluble drugs. But this field still needs more attention to new discoveries.

Conclusion: Nanosuspension contributes a crucial role in administering the different drug entities through a variety of routes involving oral, transdermal, ocular, parenteral, pulmonary, etc. with solving the different issues. This review also confirms the significance of nanosuspension in safety, efficacy, and communal as well as the economic expense associated with healthcare.

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来源期刊
Recent Patents on Drug Delivery and Formulation
Recent Patents on Drug Delivery and Formulation Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
2.30
自引率
0.00%
发文量
0
期刊介绍: Recent Patents on Drug Delivery & Formulation publishes review and research articles, drug clinical trial studies and guest edited thematic issues on recent patents on drug delivery and formulation. A selection of important and recent patents on drug delivery and formulation is also included in the journal. The journal is essential reading for all researchers involved in the fields of drug delivery and formulation. The journal also covers recent research (where patents have been registered) in fast emerging therapeutic areas/targets & therapeutic agents related to drug delivery and formulations.
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