与高血压相关的血脂异常增加冠心病的风险:雅加达国家心血管中心Harapan Kita医院的病例对照研究

IF 5.9 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Journal of Lipids Pub Date : 2019-04-30 eCollection Date: 2019-01-01 DOI:10.1155/2019/2517013
Rea Ariyanti, Besral Besral
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引用次数: 41

摘要

背景。冠心病(冠心病)是主要心血管疾病的主要亮点。在印度尼西亚,冠心病是导致死亡的主要原因,其死亡率达到26.4%,是癌症死亡率的四倍。目标。本研究旨在确定与高血压相关的血脂异常是否会增加雅加达国立心血管中心Harapan Kita医院冠心病发病率的风险。方法。研究设计为病例对照。样本为163名受访者,病例组为82名受访者,对照组为81名受访者。采用logistic回归对数据进行分析。结果。在冠心病组中,有血脂异常的受访者比例为50%,而在对照组中,有血脂异常的受访者比例为17.3%。血脂异常与冠心病发病率的关系因高血压状况而异。在年龄控制后,在高血压应答者中,血脂异常的人患冠心病的可能性是非血脂异常者的18.1倍,而在非高血压应答者中,血脂异常的人患冠心病的可能性是非血脂异常者的2.5倍。建议。建议市民定期体检,改变生活方式,健康饮食,控制血脂和血压。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dyslipidemia Associated with Hypertension Increases the Risks for Coronary Heart Disease: A Case-Control Study in Harapan Kita Hospital, National Cardiovascular Center, Jakarta.

Background. Coronary Heart Disease (CHD) is the main highlight of the major cardiovascular diseases. In Indonesia, CHD is the leading cause of death from all deaths, with rates reaching 26.4%, which is four times greater than cancer mortality rates. Objective. This study aims to determine whether dyslipidemia associated with hypertension increases the risks for the incidence of CHD in Harapan Kita Hospital, National Cardiovascular Center, Jakarta, or does not. Methods. The study design was case control. The sample was 163 respondents, 82 respondents in the case group and 81 respondents in the control group. The data were analyzed by using logistic regression. Results. In the CHD group, the percentage of respondents with dyslipidemia was 50%, while in the control group, the percentage of respondents with dyslipidemia was 17.3%. The relationship of dyslipidemia with the incidence of CHD differed according to hypertension status. After being controlled for age, in hypertensive respondents, those with dyslipidemia was 18.1 times more likely to develop CHD compared with those nondyslipidemic, whereas in nonhypertensive respondents, those with dyslipidemia was 2.5 times more likely to develop CHD compared with those nondyslipidemic. Recommendation. It is recommended that the community have medical checkup regularly and change lifestyles by taking healthy diet to control lipid profile and blood pressure.

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来源期刊
Journal of Lipids
Journal of Lipids BIOCHEMISTRY & MOLECULAR BIOLOGY-
自引率
0.00%
发文量
7
审稿时长
12 weeks
期刊介绍: Journal of Lipids is a peer-reviewed, Open Access journal that publishes original research articles and review articles related to all aspects of lipids, including their biochemistry, synthesis, function in health and disease, and nutrition. As an interdisciplinary journal, Journal of Lipids aims to provide a forum for scientists, physicians, nutritionists, and other relevant health professionals.
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