使用自动血液分析仪Sysmex XN评估未成熟血小板分数的测量结果。

Naoyuki Yoshikawa, Akiko Masuda, Masahiro Jona, Shigeo Okubo, Yasuhito Nannya, Hiromitsu Yokota, Mineo Kurokawa, Yutaka Yatomi
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引用次数: 0

摘要

未成熟血小板分数(IPF%)是网状血小板自动定量的一个参数,被认为是血小板产量的反映。我们使用自动分析仪Sysmex XN评估IPF%的测量值,我们使用XN分析仪和传统分析仪Sysmex XE测量35名健康受试者和275名不同疾病患者的血小板计数和IPF%值。XN结果与XE结果在血小板计数和IPF%之间观察到显著相关。在相同的样本中,在XN和XE结果中,血小板计数和IPF%之间观察到显著的负相关。用XN分析仪测定的血小板计数和IPF%的变异系数值低于用XE分析仪测定的。在接受造血干细胞移植的患者中,使用XN分析仪获得的IPF%测量值在血小板恢复前几天增加。使用XN分析仪进行的IPF%测量足以用于临床使用。该参数可能是预测血小板恢复的有用标记。(最初的)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Evaluation of Immature Platelet Fraction Measurements Using an Automated Hematology Analyzer, Sysmex XN].

The immature platelet fraction (IPF%) is a parameter for the automatic quantification of reticulated plate- lets and is considered to reflect platelet production. We evaluated IPF% measurements using an automated analyzer, the Sysmex XN. We measured the platelet counts and the IPF% values in 35 healthy subjects and 275 patients with various diseases using both the XN analyzer and a conventional analyzer, the Sysmex XE. Significant correlations in the platelet count and the IPF% were observed between the XN results and the XE results. In the same samples, significant inverse correlations were observed between the platelet count and the IPF% in both the XN and XE results. The coefficient of variation values for the platelet count and the IPF% measurements obtained using the XN analyzer were lower than those obtained using the XE ana- lyzer. In patients who had undergone hematopoietic stem cell transplantation, the IPF% measurements obtained using the XN analyzer increased several days before platelet recovery. IPF% measurements performed using the XN analyzer are adequate for clinical use. This parameter may be a useful marker for the prediction of platelet recovery. [Original].

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