在光催化下由苯胺合成亚砜的还原Sandmeyer型反应†

Organic chemistry frontiers : an international journal of organic chemistry Pub Date : 2023-01-01 DOI:10.1039/d3qo00297g

Gangqi Peng , Hao Cheng , Xiya Cheng , Yang He , Yuanyuan An , Jie Wu , Danqing Zheng

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引用次数: 0

摘要

报道了芳基二氮鎓盐与亚磺酸钠的还原Sandmeyer型亚磺酰基化反应。反应在光催化下进行，通过自由基取代途径产生一系列有价值的亚砜。芳香胺也可以通过一锅两步法原位重氮化转化为相应的亚砜。药物胺的后期亚磺酰基化进一步证明了该方法的实用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A reductive Sandmeyer-type reaction for the synthesis of sulfoxides from anilines under photocatalysis†

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A reductive Sandmeyer-type reaction for the synthesis of sulfoxides from anilines under photocatalysis†

A reductive Sandmeyer-type sulfinylation reaction of aryldiazonium salts with sodium sulfinates is reported. The reaction takes place under photocatalysis, generating a range of valuable sulfoxides via a radical substitution pathway. Aromatic amines can also be converted to the corresponding sulfoxides via in situ diazotization in a one-pot, two-step process. The late-stage sulfinylation of drug-based amines further demonstrated the practicality of this method.

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来源期刊

Organic chemistry frontiers : an international journal of organic chemistry

CiteScore

7.80

自引率

0.00%

发文量