继发于急性卟啉危机的非惊厥性癫痫持续状态

Sara Dawit , Shubhang K. Bhatt , Devika M. Das , Andrew R. Pines , Harn J. Shiue , Brent P. Goodman , Joseph F. Drazkowski , Joseph I. Sirven
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引用次数: 5

摘要

多样和急性间歇卟啉症均可表现为各种神经系统症状。虽然急性症状性发作以前也有过描述,但它们通常是强直-阵挛和局灶性意识受损发作。惊厥性癫痫持续状态和部分持续性癫痫是罕见的,并在病例报告的基础上进行了描述。据我们所知,以前没有报道的病例描述非惊厥癫痫持续状态(NCSE)与脑电图(EEG)记录在急性卟啉症危象的设置。我们报告了一个独特的NCSE表现,在给予左乙拉西坦后解决了一个患有多种卟啉症的患者,没有已知的癫痫发作障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Nonconvulsive status epilepticus secondary to acute porphyria crisis

Nonconvulsive status epilepticus secondary to acute porphyria crisis

Nonconvulsive status epilepticus secondary to acute porphyria crisis

Nonconvulsive status epilepticus secondary to acute porphyria crisis

Both variegate and acute intermittent porphyria can manifest with various neurological symptoms. Although acute symptomatic seizures have been previously described, they are typically tonic–clonic and focal impaired awareness seizures. Convulsive status epilepticus and epilepsia partialis continua are rare and have been described on a case report basis. To our knowledge, there are no previously reported cases describing non-convulsive status epilepticus (NCSE) with electroencephalogram (EEG) documentation in the setting of acute porphyria crisis. We report a unique presentation of NCSE, which resolved after administering levetiracetam in a patient with variegate porphyria, without a known seizure disorder.

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