农业动物作为生物医学模型:职业健康和安全考虑。

IF 3.1 3区农林科学 Q1 VETERINARY SCIENCES

Ilar Journal Pub Date : 2018-12-31 DOI:10.1093/ilar/ily013

Gaylen L Edwards, Michael J Azain, Andrew Parks

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引用次数: 6

摘要

农业动物在生物医学研究中的使用正在增加。它们的总体大小和代谢率、器官大小、较长的妊娠期和其他生理上的相似性使它们成为人类疾病动物模型的良好候选者。使用传统农场动物进行生物医学研究有一些特殊的考虑。在将传统农场动物用于生物医学研究时，在工厂物理基础设施、处理设备、人员培训和潜在的人畜共患病方面的差异是一些重要的考虑因素。本文概述了在生物医学研究中使用传统农业动物的一些特殊考虑。随着对改进转化研究的需求日益增长，预测这些动物模型的显著增长是合理的。

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Agricultural Animals as Biomedical Models: Occupational Health and Safety Considerations.

The use of agricultural animals in biomedical research is increasing. Their overall size and metabolic rate, organ size, longer gestation period, and other physiological similarities make them good candidates for animal models of human disease. There are a number of special considerations for use of traditional farm animals for biomedical research. Differences in physical plant infrastructure, handling equipment, training of personnel, and potential zoonoses are some of the important considerations when traditional farm animals are used in biomedical research. This article provides an overview of some of the special considerations for using traditional agricultural animals in biomedical research. With the growing need for improved translational research, it is reasonable to predict significant growth in these animal models.

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来源期刊

Ilar Journal 农林科学-兽医学

CiteScore

5.10

自引率

20.00%

发文量

审稿时长

>18 weeks

期刊介绍： The ILAR Journal is the peer-reviewed, theme-oriented publication of the Institute for Laboratory Animal Research (ILAR), which provides timely information for all who study, use, care for, and oversee the use of animals in research. The journal publishes original articles that review research on animals either as direct subjects or as surrogates for humans. According to policy, any previously unpublished animal research reported in the ILAR Journal will have been conducted according to the scientific, technical, and humanely appropriate guidelines current at the time the research was conducted in accordance with the Guide for the Care and Use of Laboratory Animals or other guidance provided by taxonomically-oriented professional societies (e.g., American Society of Mammalogy) as referenced in the Guide.