曲霉属真菌的次生代谢物及其在化学系统学中的应用

Mikrobiologiia Pub Date : 2017-03-01

A G Kozlovskii, T V Antipova, V P Zhelifonova, B P Baskunov, N E Ivanushkina, G A Kochkina, S M Ozerskaya

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引用次数: 0

摘要

研究了22株真菌(Aspergillus属，section Usti)在不同地理区域(包括北极永久冻土带)分离的次生代谢物。所研究的菌株合成多种生物活性化合物，结构鉴定为drimane倍半萜类、异喹啉类生物碱(TMC-120 a−C，衍生物1)、meroterpenoids (austalides О和J)和蒽醌色素(averufin, versicolorin C)。利用次级代谢产物的个体光谱对17株菌株进行了再鉴定，其中15株鉴定为假偏转棘球蚴，2株鉴定为假偏转棘球蚴。

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[Secondary Metabolites of Fungi of the Usti Section, Genus Aspergillus and Their Application in Chemosystematics].

Secondary metabolites of 22 fungal strains (genus Aspergillus, section Usti) isolated at diverse geographic regions, including the Arctic permafrost deposits, were studied. The studied strains were found to synthesize a variety of biologically active compounds, structurally identified as drimane sesqueterpenoids, isoquinoline alkaloids (TMC-120 A−C, derivative 1), meroterpenoids (austalides О and J), and anthraquinone pigments (averufin, versicolorin C). Desferritriacetylfusigen production by A. calidoustus isolates is reported for the first time. The individual spectra of secondary metabolites were used for reidentification of 17 strains, of which 15 were identified as A. calidoustus and two, as A. pseudodeflectus.

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Mikrobiologiia

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