E P Ryzhkovaa, I L Shamraichuk, A V Kurakov, A I Netrusov
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[Production of Antimicrobial Polypeptides by Propionibacterium freudenreichii RVS-4-irf].
Propionibacterium freudenreichii RVS-4-irf is a probiotic bacterium producing antimicrobial
exometabolites applicable for foodstuff protection. Production of antimicrobial factors other than lowmolecular
propionates was observed in media with and without trypton. A method was developed for production
of the fraction of high-molecular mass exopolymers from the culture liquid. Their polypeptide nature was
confirmed using proteinase K. The preparation of extracellular polypeptides from P. freudenreichii RVS-4-irf
exhibited species-specific activity in suppression of fungal and bacterial growth.