M B Plotnikov, O I Aliev, A M Anishchenko, A B Sidekhmenova, A Yu Shamanaev, T I Fomina
{"title":"[SHR大鼠动脉高血压和稳健性高血压发展过程中大脑皮层毛细血管网络参数]。","authors":"M B Plotnikov, O I Aliev, A M Anishchenko, A B Sidekhmenova, A Yu Shamanaev, T I Fomina","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The studies were performed in hypertensive rats (SHR strain) during the period of hypertension development (7-8 weeks) and stable high blood pressure (16-17 weeks) and in normotensive rats (WKY strain) of corresponding ages. The average number of capillaries per square millimeter, the average capillaries diameter, and the capillary network structure following the estimation of capillaries distribution based on capillaries diameter within the following ranges (up to 3, from 3 to 5, from 5 to 7 and from 7 to 9 μm) were investigated using the morphological approach. The average diameter of capillaries and capillary network structure in SHRs during the development of hypertension did not differ from the respective values in WKY rats of the same age. SHR rats showed disturbed microvascularisation by structural and functional rarefaction in the stable high blood pressure period, which was manifested in lower average capillaries density and average capillaries diameter as well as in substantial (2.5 times) increase in plasmatic capillaries as compared to WKY rats of the same age.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"102 5","pages":"558-66"},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[PARAMETERS OF CEREBRAL CORTEX CAPILLARY NETWORK IN SHR RATS DURING THE DEVELOPMENT OF ARTERIAL HYPERTENSION AND STABLE HIGH BLOOD PRESSURE].\",\"authors\":\"M B Plotnikov, O I Aliev, A M Anishchenko, A B Sidekhmenova, A Yu Shamanaev, T I Fomina\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The studies were performed in hypertensive rats (SHR strain) during the period of hypertension development (7-8 weeks) and stable high blood pressure (16-17 weeks) and in normotensive rats (WKY strain) of corresponding ages. The average number of capillaries per square millimeter, the average capillaries diameter, and the capillary network structure following the estimation of capillaries distribution based on capillaries diameter within the following ranges (up to 3, from 3 to 5, from 5 to 7 and from 7 to 9 μm) were investigated using the morphological approach. The average diameter of capillaries and capillary network structure in SHRs during the development of hypertension did not differ from the respective values in WKY rats of the same age. SHR rats showed disturbed microvascularisation by structural and functional rarefaction in the stable high blood pressure period, which was manifested in lower average capillaries density and average capillaries diameter as well as in substantial (2.5 times) increase in plasmatic capillaries as compared to WKY rats of the same age.</p>\",\"PeriodicalId\":21358,\"journal\":{\"name\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"volume\":\"102 5\",\"pages\":\"558-66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[PARAMETERS OF CEREBRAL CORTEX CAPILLARY NETWORK IN SHR RATS DURING THE DEVELOPMENT OF ARTERIAL HYPERTENSION AND STABLE HIGH BLOOD PRESSURE].
The studies were performed in hypertensive rats (SHR strain) during the period of hypertension development (7-8 weeks) and stable high blood pressure (16-17 weeks) and in normotensive rats (WKY strain) of corresponding ages. The average number of capillaries per square millimeter, the average capillaries diameter, and the capillary network structure following the estimation of capillaries distribution based on capillaries diameter within the following ranges (up to 3, from 3 to 5, from 5 to 7 and from 7 to 9 μm) were investigated using the morphological approach. The average diameter of capillaries and capillary network structure in SHRs during the development of hypertension did not differ from the respective values in WKY rats of the same age. SHR rats showed disturbed microvascularisation by structural and functional rarefaction in the stable high blood pressure period, which was manifested in lower average capillaries density and average capillaries diameter as well as in substantial (2.5 times) increase in plasmatic capillaries as compared to WKY rats of the same age.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
