{"title":"红细胞微泡对血小板聚集的影响。","authors":"G Ya Levin, E G Sukhareva","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We studied the influence of erythrocyte microvesicles, isolated after 4 weeks incubation the washed and the unwashed erythrocytes healthy donors from preservative, on spontaneous (flow-induced) aggregation of platelets. It was found out that microvesicles of the unwashed erythrocytes enhanced the spontaneous aggregation of platelets and also formation of fibrin. Microvesicles from the washed erythrocytes reduce the platelet aggregation. Possible mechanisms of the effect of erythrocyte microvesicles on platelet aggregation were investigated.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"102 8","pages":"968-75"},"PeriodicalIF":0.0000,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[THE EFFECT OF ERYTHROCYTE MICROVESICLES ON THE AGGREGATION OF PLATELETS].\",\"authors\":\"G Ya Levin, E G Sukhareva\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We studied the influence of erythrocyte microvesicles, isolated after 4 weeks incubation the washed and the unwashed erythrocytes healthy donors from preservative, on spontaneous (flow-induced) aggregation of platelets. It was found out that microvesicles of the unwashed erythrocytes enhanced the spontaneous aggregation of platelets and also formation of fibrin. Microvesicles from the washed erythrocytes reduce the platelet aggregation. Possible mechanisms of the effect of erythrocyte microvesicles on platelet aggregation were investigated.</p>\",\"PeriodicalId\":21358,\"journal\":{\"name\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"volume\":\"102 8\",\"pages\":\"968-75\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[THE EFFECT OF ERYTHROCYTE MICROVESICLES ON THE AGGREGATION OF PLATELETS].
We studied the influence of erythrocyte microvesicles, isolated after 4 weeks incubation the washed and the unwashed erythrocytes healthy donors from preservative, on spontaneous (flow-induced) aggregation of platelets. It was found out that microvesicles of the unwashed erythrocytes enhanced the spontaneous aggregation of platelets and also formation of fibrin. Microvesicles from the washed erythrocytes reduce the platelet aggregation. Possible mechanisms of the effect of erythrocyte microvesicles on platelet aggregation were investigated.