衰老相关的虚弱和肌肉减少症。骨质疏松治疗药物对虚弱和肌肉减少症的疗效。

Clinical calcium Pub Date : 2018-01-01 DOI:CliCa180912631267

Tsuyoshi Watanabe, Yasumoto Matsui

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引用次数: 0

摘要

许多虚弱的不良后果可能是由肌肉减少症介导的。不幸的是，目前还没有批准的药物治疗肌肉减少症。骨质疏松症和肌肉减少症在老年人中很常见。一项关于活化维生素D的研究表明，骨质疏松症患者服用阿法骨化醇可以维持肌肉质量。双膦酸盐疗法是治疗骨质疏松症的黄金标准，可能有助于维持肌肉质量。

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[Aging-related frailty and sarcopenia. Efficacy of osteoporosis treatment drugs for frailty and sarcopenia.]

Many of the adverse outcomes of frailty are probably mediated by sarcopenia. Unfortunately, there are currently no approved drug treatments for sarcopenia. Osteoporosis and sarcopenia are common in older age. A study on activated vitamin D revealed that muscle mass could be maintained by administering alfacalcidol to patients with osteoporosis. Bisphosphonate therapy, which is a gold standard for osteoporosis treatment, may help to maintain muscle mass.

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Clinical calcium

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