[抗nmdar脑炎作为一种严重不良事件可能与黄热病疫苗接种有关]。

Q3 Medicine
Lubomíra Hozáková, Jana Slonková, Šárka Blahutová
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引用次数: 0

摘要

我们报告了一例17岁的女性与抗nmdar脑炎可能与黄热病疫苗接种有关。她在接种黄热病疫苗27天后出现症状。抗nmdar脑炎表现为急性精神病、记忆丧失和发烧后紧张症并伴有复杂的部分癫痫发作。间期脑电图显示慢波三角洲背景活动,伴有“三角洲刷”。血清及脑脊液NMDAR抗体阳性证实诊断。由于卵巢畸胎瘤作为抗nmdar脑炎最常见的病因,在发病后5年内未发生,因此与黄热病疫苗接种的关联似乎极有可能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Anti-NMDAR encephalitis as a serious adverse event probably related to yellow fever vaccination].

We present a case of a 17-year-old female with anti-NMDAR encephalitis probably associated with vaccination against yellow fever. Her symptoms occurred 27 days after vaccination against yellow fever. Anti-NMDAR encephalitis manifested as acute psychosis, memory loss and catatonia following fever with complex partial epileptic seizures. Interictal electroencephalogram showed slow-wave delta background activity with "delta brushes". The diagnosis was confirmed by NMDAR antibody positivity in serum and cerebrospinal fluid. Since ovarian teratoma, as the most common cause of anti-NMDAR encephalitis, did not develop within five years from its onset, the association with vaccination against yellow fever seems to be highly probable.

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来源期刊
Klinicka mikrobiologie a infekcni lekarstvi
Klinicka mikrobiologie a infekcni lekarstvi Medicine-Infectious Diseases
CiteScore
0.40
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