Swarupa M Hatolkar, Rabindra N Misra, Rajesh Mahato, Savita Jadhav
{"title":"印度浦那北京基因型结核分枝杆菌肺外临床耐药分离株的全基因组测序和注释。","authors":"Swarupa M Hatolkar, Rabindra N Misra, Rajesh Mahato, Savita Jadhav","doi":"10.1128/genomeA.00504-18","DOIUrl":null,"url":null,"abstract":"<p><p>Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among <i>Mycobacterium tuberculosis</i> isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the <i>Mycobacterium tuberculosis</i> complex (MTC)-Beijing genotype circulating in Maharashtra, India, which was obtained from the cerebrospinal fluid (CSF) of an immunocompetent patient, was subjected to whole-genome sequencing.</p>","PeriodicalId":12619,"journal":{"name":"Genome Announcements","volume":"6 25","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/genomeA.00504-18","citationCount":"1","resultStr":"{\"title\":\"Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India.\",\"authors\":\"Swarupa M Hatolkar, Rabindra N Misra, Rajesh Mahato, Savita Jadhav\",\"doi\":\"10.1128/genomeA.00504-18\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among <i>Mycobacterium tuberculosis</i> isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the <i>Mycobacterium tuberculosis</i> complex (MTC)-Beijing genotype circulating in Maharashtra, India, which was obtained from the cerebrospinal fluid (CSF) of an immunocompetent patient, was subjected to whole-genome sequencing.</p>\",\"PeriodicalId\":12619,\"journal\":{\"name\":\"Genome Announcements\",\"volume\":\"6 25\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1128/genomeA.00504-18\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Genome Announcements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1128/genomeA.00504-18\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Genome Announcements","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/genomeA.00504-18","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India.
Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among Mycobacterium tuberculosis isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the Mycobacterium tuberculosis complex (MTC)-Beijing genotype circulating in Maharashtra, India, which was obtained from the cerebrospinal fluid (CSF) of an immunocompetent patient, was subjected to whole-genome sequencing.